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Sheridan Grant

Content Specialist

Sheridan is a writer from Hamilton, Ontario. She has a passion for writing about what she loves and learning new things along the way. Her topics of expertise include skincare and beauty, home decor, and DIYing.

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About Thesis Nootropics

Hands up if you guzzle five coffees a day to stay awake, have tried all the supplements in the book desperate to improve your headspace, and aren’t interested in prescribed medications. Designed to increase focus , Thesis nootropics might be for you. 

Thesis offers a customized blend of ingredients designed to optimize your cognitive function , with personalized details that tackle your specific needs. Nootropics boost brain performance in the same way a stimulant would, without the common negative effects. 

A study published in the Journal of Alzheimer’s Disease found that nootropics may help improve cognitive function in people with Alzheimer’s disease.

Interested in finding out more about the brand and how it works? Leaf through our Thesis Nootropics review. We’ll be your guide through the company and the process, as well as details on the treatments, highlights from customer reviews, answers to important FAQs, and more, to help you decide if it’s worth the try.

Pros and Cons

• Multiple cognitive benefits: Thesis Nootropics offers a variety of blends that cater to multiple aspects of cognitive function.
• Long-term effects: On top of short term benefits for daily life, Thesis nootropics ingredients are designed to impact the brain in the long-term.
• Personalized recommendations: Thesis Nootropics makes personalized recommendations based on your goals and unique brain chemistry.
• Potential side effects: The most common side effects to watch out for when you start taking Thesis Nootropics include heartburn, headaches, confusion, dizziness, loss of appetite, and digestive issues.
• Need to stop taking if issues arise: If you experience a headache or an upset stomach that won’t go away while taking their nootropics, Thesis recommends that you stop taking them.

What is Thesis Nootropics?

Nootropics are nutrient compounds and substances that are known to improve brain performance , such as caffeine and creatine. They help with issues that affect motivation, creativity, mood, memory, focus, and cognitive processing.

Nootropics are the ideal addition to an already healthy lifestyle that consists of exercise, proper nutrition, and enjoyable activities.  Thesis nootropics are carefully formulated to target specific needs, ranging from energy to creativity. The brand focuses on safety, ensuring that all supplements adhere to FDA guidelines and go through multiple clinical trials. 

How Thesis Nootropics Works

With all that being said, you may be wondering how Thesis provides users with an option that is specific to their needs. Fortunately, the process is simple and hassle free. Here’s how it works:

• Take the Thesis nootropics quiz
• Answer questions about your basic information
• Receive personalized recommendations 
• Get your starter kit for $120 , or $79 monthly when you subscribe 

After that, you’ll select one formula to take each week, taking one day off in between each different option. You’ll also track your results in the daily journal over the month to see how they affect your daily life. 

From there, it operates as a subscription service. Users will be able to optimize their next shipment by telling the brand which formulas worked best.

If you don’t like any of the blends in your box, let the company know and they’ll switch it for something that’s a better fit for your lifestyle, genetics, and goals.

Thesis Nootropics Ingredients

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties. Here are some of the key ingredients in Thesis Nootropics:

• Cognizin (Citicoline) : Cognizin is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
• L-Theanine : L-Theanine is an amino acid that is found in green tea, and is known for its ability to promote relaxation and reduce stress and anxiety.
• Lion’s Mane Mushroom : Lion’s Mane Mushroom is a type of medicinal mushroom that is believed to have cognitive-boosting properties, including improved memory and focus.
• Rhodiola Rosea : Rhodiola Rosea is an adaptogenic herb that is known for its ability to reduce stress and fatigue, and improve mental clarity and cognitive function.
• Ashwagandha : Ashwagandha is an adaptogenic herb that is known for its ability to reduce stress and anxiety, and improve memory and cognitive function.
• Phosphatidylserine : Phosphatidylserine is a type of phospholipid that is found in high concentrations in the brain, and is believed to support cognitive function, including memory and focus³
• Alpha-GPC : Alpha-GPC is a type of choline that is known for its ability to enhance cognitive function, including memory and focus.
• TAU (uridine): TAU is a blend of uridine, choline, and DHA, which is believed to support brain health and cognitive function.
• Artichoke extract : Artichoke extract is believed to enhance cognitive function by increasing levels of acetylcholine, a neurotransmitter that is important for memory and learning.
• Dynamine : Dynamine is a type of alkaloid that is believed to enhance cognitive function by increasing levels of dopamine, a neurotransmitter that is important for mood and motivation.

Overall, the ingredients in Thesis Nootropics are carefully chosen for their cognitive-boosting properties, and are designed to work together to enhance overall brain health and cognitive function.

Thesis Nootropics Health Benefits

Thesis Nootropics is a brand that offers personalized nootropics designed to enhance cognitive function and overall brain health. Their blends contain a variety of ingredients that are carefully chosen for their cognitive-boosting properties, and offer numerous health benefits. Here are some of the health benefits of Thesis Nootropics:

• Increased cognitive energy : One of the key benefits of Thesis Nootropics is increased cognitive energy, which can help improve productivity, mental alertness, and motivation, as it contains cognizin .
• Enhanced mental clarity : Another benefit of Thesis Nootropics is enhanced mental clarity,given from Lion’s Mane Mushroom which can help reduce brain fog and improve focus.
• Improved memory and learning abilities : Thesis Nootropics contains ingredients that are believed to improve memory and learning abilities, like Phosphatidylserine , which can help users retain information more effectively.
• Elevated mood : Thesis Nootropics may help elevate mood and reduce symptoms of anxiety and depression, thanks to ingredients like L-Theanine and Ashwagandha .
• Lowered stress levels : The adaptogenic herbs in Thesis Nootropics, such as Rhodiola Rosea and Ashwagandha , are known for their ability to lower stress levels and promote relaxation.
• Boosted focus : Thesis Nootropics contains ingredients like Alpha-GPC and Artichoke extract , which are believed to boost focus and concentration.

While Thesis Nootropics offers numerous health benefits, it’s important to note that the long-term effects of nootropics are not yet fully understood and more research is needed.

3 Thesis Nootropics Bestsellers

Thesis energy review.

If you’re constantly struggling to keep up with the demands of your busy life, it might be time to try a natural energy booster like Thesis Energy. This powerful nootropic blend is specifically designed to increase energy, overcome fatigue, and build mental stamina.

Thesis Energy is caffeine-free, making it a great option for those who are sensitive to caffeine or looking for a natural alternative to traditional energy drinks. The Energy formulation is designed to help improve focus and mental clarity, increase cognitive energy, and reduce fatigue. Whether you’re facing a busy day at work, recovering after a night of poor sleep, or gearing up for an intense workout, Thesis Energy can help you power through.

Each ingredient in Thesis Energy is carefully chosen for its energy-boosting properties. The specific ingredients can vary depending on your needs, but they work together to help increase energy, improve mental clarity, and reduce fatigue.

To get the most out of Thesis Energy, take it every morning on an empty stomach. You can also take it again after lunch if you need an extra boost. It’s designed to help you tackle busy, hectic days, recover from poor sleep, and power through intense workouts.

If you’re tired of relying on coffee and energy drinks to get through the day, it might be time to give Thesis Energy a try. Check availability and start boosting your energy naturally today!

Thesis Creativity

If you’re someone who struggles with creativity or finds yourself feeling stuck in your creative endeavors, Thesis Creativity may be worth considering. This nootropic supplement is designed to help spark inspiration, enhance verbal fluency, and boost confidence in your own great ideas.

So what’s in Thesis Creativity? The ingredients may vary depending on your specific needs, but these ingredients work together to support stress management, memory function, mood regulation, and energy production.

By supporting stress management, memory function, and mood regulation, Thesis Creativity can help free up mental space for more creative thinking. Additionally, the caffeine and L-theanine combo can provide a boost of energy and focus without the jitters and crash that can come with caffeine alone.

To get the most out of Thesis Creativity, it is recommended to take it every morning on an empty stomach and again after lunch if you need an extra boost. This nootropic blend is particularly helpful for brainstorming and creative thinking, writing and creative projects, and public speaking and social situations.

As with any nootropic supplement, it’s important to note that the long-term effects of Thesis Creativity are not yet fully understood and more research is needed. It’s always a good idea to speak with a healthcare professional before adding any new supplements to your routine.

In summary, if you’re looking for a little extra help in the creativity department, Thesis Creativity may be a valuable addition to your nootropic lineup. Its unique blend of ingredients can help support mental clarity, mood regulation, and energy production, making it a valuable tool for any creative individual.

Thesis Logic

If you’ve been having trouble with your memory lately, such as forgetting what you had for lunch yesterday or struggling to recall common words, then Thesis Logic may be just what you need. This formula is designed to help enhance your processing speed, boost your memory, and deepen your thinking.

Thesis Logic is caffeine-free, making it a great option for those who are sensitive to caffeine. The formula is ideal for use during deep, focused work, complex problem-solving, research projects, and completing tedious tasks.

Taking Thesis Logic is easy – simply take it every morning on an empty stomach, and take it again after lunch if you need an extra boost. By incorporating Thesis Logic into your daily routine, you may notice improvements in your cognitive function and overall mental performance.

Who Is Thesis Nootropics For? 

Thesis nootropics are designed for a number of different specific needs, including anyone who wants to focus better, have more energy, and maintain mental clarity. All in all, the products are specifically formulated to improve day to day life and target your specific needs .

Thesis Nootropics Side Effects

While Thesis nootropics are designed to enhance cognitive performance and provide a range of benefits, it’s important to be aware of the potential side effects that can occur. As with any supplement, individual reactions can vary, and some people may experience side effects while others may not.

Some of the potential side effects of Thesis nootropics include:

• Insomnia : Some nootropics contain caffeine or other stimulants that can disrupt sleep patterns and lead to difficulty falling asleep or staying asleep.
• Blurry vision : Certain nootropics, such as those containing alpha GPC, have been linked to temporary blurry vision.
• High blood pressure : Stimulant-based nootropics can increase blood pressure, which can be dangerous for people with hypertension or other heart conditions.
• Fast heart rate : Similarly, stimulants can also increase heart rate, leading to palpitations or a rapid pulse.
• Circulation problem s: Certain nootropics, such as vinpocetine, can affect blood flow and circulation, leading to issues like dizziness, nausea, or headaches.
• Addiction : Some nootropics, such as those containing racetams, have been associated with the potential for addiction or dependence if used long-term.

It’s important to remember that not all nootropics will produce these side effects, and the severity of any reactions will depend on individual factors such as dosage, duration of use, and underlying health conditions. However, it’s always wise to discuss any potential risks with a healthcare professional before starting any new supplement regimen.

Additionally, it’s important to follow dosage instructions carefully and not to exceed recommended amounts, as this can increase the risk of side effects. By being mindful of potential risks and using nootropics responsibly, users can reap the benefits of these supplements without experiencing adverse effects.

Thesis Nootropics Reviews: What Do Customers Think?

At this point in our Thesis nootropics review, it’s time to turn to what customers are saying. So, we sourced testimonials from the brand’s website, Reddit, and ZenMasterWellness. And spoiler alert, the Thesis nootropics reviews we came across have nothing but good things to say.

On takethesis.com , the brand earns 4.4/5 stars out of 7,956 reviews. One patron describes their particular blend as the perfect alternative to prescription meds :

“ I have been off stimulants for months now and these formulas are far superior. My husband and daughter both noticed the change and said I have been more productive, focused, less anxious, and more “thinking outside the box”. I have tried for years to get off stims and nothing would work .”

On Reddit, many reviewers share similar sentiments about how effective the products are. One buyer shares that they tried tons of different nootropics on the market, and Thesis stands out amongst the crowd . 

On ZenMasterWellness, one reviewer states that their blend provided the exact results they were looking for :

“ They offer notable improvements to how well I’m able to focus, stay on task, and grind when it’s time to grind. In practice, this usually looks like a clearer mind and an improved ability to just… chill. With the Clarity and Creativity blends, in particular, I just feel leveled out .”

Backed by clinical trials and real customer experiences, Thesis stands out in the world of nootropics and supplements. The personalized selections prove effective, while the quality ingredients live up to expectations. 

Is Thesis Nootropics Legit?

If you’re wondering if this brand offers products that are too good to be true, this Thesis nootropics review is here to say that it is the real deal .

The brand is backed by numerous clinical trials, which highlight how 86% of customers reported improvements in a wide range of cognitive challenges, while 89% noticed an improvement in their ability to reduce stress and maintain energy.

Is Thesis Nootropics Worth It?

Thesis is an appealing choice in the world of nootropics because it provides a completely customized selection based on your needs and goals. Plus, the ingredients are potent and ensure the best effects—and you only end up paying for the benefits you actually need.

With that in mind, this Thesis nootropics review deems the brand worth the try.

Alternatives

Here are some alternatives to Thesis Nootropics that you might find interesting:

• Mind Lab Pro – This nootropic supplement is designed to improve cognitive function and mental performance. It contains 11 ingredients that work together to enhance memory, focus, and overall brain health.
• Thorne Supplements : If you’re looking for high-quality, science-based supplements, Thorne is a great choice. Their products are designed with the latest research in mind and are rigorously tested for quality and purity. Some of their popular offerings include multivitamins, protein powders, and omega-3 supplements.
• WeAreFeel Supplements : WeAreFeel is a supplement brand that offers a variety of products designed to support different aspects of your health. Their supplements are vegan-friendly and free from artificial colors, flavors, and preservatives. Some of their popular offerings include multivitamins, probiotics, and omega-3 supplements.
• Neuro Gum : If you’re looking for a quick and easy way to boost your focus and energy levels, Neuro Gum is a great option. This gum is infused with caffeine and other natural ingredients that can help improve mental clarity and alertness. Plus, it’s sugar-free and comes in a variety of delicious flavors.
• Neuriva Plus : Neuriva Plus is a brain supplement that’s designed to improve memory, focus, and cognitive performance. It contains a blend of natural ingredients, including coffee fruit extract and phosphatidylserine, that have been shown to support brain health. If you’re looking for a natural way to boost your cognitive function, Neuriva Plus is worth considering.

Thesis Nootropics Promotions & Discounts 

There aren’t currently any Thesis promos or discounts available. That being said, if you subscribe for recurring shipments of your recommended products, you’ll save $40 monthly .

Where to Buy Thesis Nootropics

At the time of this Thesis nootropics review, the products are exclusively available on the brand’s website, takethesis.com .

Is Thesis Nootropics vegan?  

Thesis nootropics are made with only vegan ingredients . That being said, while the brand has taken precautions to protect against cross contamination, the products are not certified vegan.

Is Thesis Nootropics gluten-free? 

On top of being vegan, Thesis products are made without gluten, eggs, or nuts . Again, while the brand strives to protect users against cross contamination, the products are not certified gluten free. 

What is Thesis Nootropics’ Shipping Policy?

If you’re anxiously awaiting your order from this Thesis nootropics review, you’ll be happy to hear that the company offers speedy shipping, sending orders out within 1 business day. After that, packages should arrive within only 1-3 business days . Costs are calculated at checkout.

At this time, Thesis is not able to offer international shipping. This Thesis nootropics review recommends following the brand on social media and signing up for the newsletter to stay up to date with shipping policies. 

What is Thesis Nootropics’ Return Policy?

If you find that your Thesis formula isn’t working out, the company requests that you contact them to make changes and adjustments to ensure you are able to receive the proper help.

If you would still like to make a return, follow these simple steps for a refund:

• Submit your refund request
• Ship the items back within 30 days of the original delivery
• Send an email with your tracking number to the brand
• Return any remaining product in their original packaging to: 

Thesis Returns 902 Broadway

6th Floor New York, NY 

Once your return has been received, a refund will be processed and email confirmation will be sent. It’s also important to note that the brand can only refund one month’s supply per customer and return shipping is the customer’s responsibility. 

How to Contact Thesis Nootropics

We hope you enjoyed this Thesis nootropics review! If you have any further questions about the brand or its products, you can contact them using the following methods:

• Call 1 (646) 647-3599
• Email [email protected]

902 Broadway Floor 6 New York, NY 10010

If you’re looking for other ways to boost your productivity via supplements, check out these other brands we’ve reviewed:

Thorne Supplements Review

WeAreFeel Supplements Review

Neuro Gum Review

Neuriva Plus Review

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Thesis Nootropics Review

Thesis has a range of targeted nootropics you can combine to optimize your results. our team will help you decide which ones are right for you..

Daniel is a senior editor and writer at Innerbody Research. After receiving his bachelor’s degree in writing, he attended post-graduate studies at George Mason University and pursued a career in nutritional science.

Dr. Segar is a cardiologist at the Texas Heart Institute and a member of Innerbody Research's Medical Review Board.

In this Review

Nootropics in general offer the potential to improve cognitive abilities and regulate mood without the need for a prescription. And while more research is necessary, current data suggests that they consist of ingredients that are generally safe and effective for healthy adults. 35 However, Thesis isn’t the only provider of high-quality nootropics, nor do they offer especially low prices. In this review, we'll compare and contrast Thesis’ six formulas and see how they stack up against a growing field of competitors.

Our Findings

• You can feel most results within an hour
• Products are third-party-tested for purity
• All options available without stimulants
• Outstanding phone support
• Subscriptions include complimentary wellness coaching
• Free shipping on all orders
• Use code INNERBODY for 10% off your first order
• Somewhat more expensive than competitors
• Up to four large pills per dose

Despite the somewhat high price, we recommend Thesis to anyone looking for a nootropic subscription that can be tailored to their specific needs. The formulas from Thesis provide tangible benefits with minimal ingredients, and each formula is available with or without caffeine. Thesis also offers stellar customer service and delivers their product in individually packed doses you can take just about anywhere.

Special Offer: Take 10% OFF with code INNERBODY

Why you should trust us

Over the past two decades, Innerbody Research has helped tens of millions of readers make more informed decisions about staying healthy and living healthier lifestyles. As nootropics have become more important players in the supplements landscape, we’ve taken a serious look at the key players to see which ones are worthwhile.

Thesis exists in a class of nootropics that combines multiple nootropic ingredients to achieve specific goals. We’ve spent hundreds of hours researching and testing various nootropics, including both individual ingredients and combinations like Thesis offers. In researching Thesis and their competitors, our team has read more than 100 clinical studies examining the efficacy and safety of nootropic ingredients, and we’ve combined all of that knowledge with our experiences to create this review.

If you're curious about our team's experience using Thesis nootropics and wondering how the products will arrive at your door, we made this handy, 5-minute video summarizing those details:

Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy.

How we evaluated Thesis

To evaluate Thesis, we examined the extensive research available on each ingredient the company uses and compared them to a growing marketplace of nootropics, many of which our testing team has tried over the past few years. Specifically, we assessed how effectively Thesis' formulas work, as well as their safety, cost, and the convenience of acquiring and taking them.

Ultimately, we found Thesis to be one of the more reliable companies in terms of product quality and customer care, even if they are among the more expensive nootropic brands. For any nootropic, you’re looking to create a noticeable effect in brain performance, and altering anything to do with that sensitive chemistry likely warrants a fair investment. The bargain bin is not typically where you want to shop for mind-enhancing substances.

We’ll get into a more direct comparison between Thesis and their competitors a little later, and you’ll see that the balance between their price and overall value is quite reasonable. For now, let’s look at each criterion in more detail.

Effectiveness

Nootropic companies have a plethora of ingredients at their fingertips when they formulate their products. Some companies take a modern approach, focusing on the latest research into established Western medicines. Others look to the past, where ancient Chinese and Ayurvedic practices employed various botanicals to achieve cognitive effects. The best companies combine these approaches, using potentially beneficial ingredients that science supports.

Thesis takes this combined approach, employing just under three dozen ingredients from amino acids to ancient herbs across their six products. The company scores highly in effectiveness thanks to the ingredients they choose and the doses they offer for each, making it likely that you can notice their combined effects.

Individual results will vary due to everything from sleep patterns to diet, but most people should find benefits in at least one of Thesis' six formulas. Caffeinated formulas generally have more pronounced effects than stimulant-free versions, but the value of Thesis offering every formula with or without stimulants cannot be overstated.

One minor knock against Thesis is that, unlike some of their competitors, Thesis does not have a nootropic blend designed for improved sleep. Better sleep supports cognition and mood, so some companies offer formulas designed specifically for sleep promotion with ingredients like melatonin. That said, some of Thesis’ formulas contain lion’s mane or Zembrin (a branded form of Sceletium tortuosum that’s been shown to reduce anxiety and promote sleep). 2 3 And the amount of Zembrin used in Thesis’ Creativity and Confidence blends is the exact same amount used in these successful studies — 25mg.

Good nootropics are, unfortunately, a bit expensive. You can find less expensive options than Thesis, but their $79 monthly rate is right in the middle of what the market demands. You could also argue that the ingredient quality, customization options, and overall efficacy Thesis offers make it a superior value to many less expensive alternatives. Still, the price remains a sticking point for some.

Let's compare the monthly and per-dose costs with some of Thesis' closest competition. The prices below reflect subscription savings where available.

Three of the seven competitors included in the chart above are more expensive than Thesis, and another three are no more than $15 less expensive, revealing their generally average cost. Focus Factor — consistently our top budget pick among nootropics — costs much less than others in the field and includes many ingredients with associated clinical research. The downside is that increasing the number of ingredients (even when they seem to work) increases the odds of an adverse reaction.

TruBrain is the only company that truly compares to Thesis from a quality and variety standpoint. Other companies offer only one or two formulas, whereas Thesis and TruBrain each offer several more targeted products. TruBrain allows you to spend just $69 on your first jar when you subscribe — $10 less than Thesis — but that price shoots up to $119 every month after that, making Thesis the superior value.

When we consider the safety of any supplement, we look at available research into individual ingredients and compare those dosages with what the supplement offers. Whenever possible, we also test the product ourselves to observe its effects on us. Additionally, we look for safety standards in manufacturing that can provide added peace of mind, like third-party testing and compliance with the FDA’s Good Manufacturing Practices (GMP).

Thesis manufactures their products in GMP-compliant facilities and has third-party testing performed to assess the purity of each ingredient and formula. And the clinical research involving the lion's share of their ingredients reveals minimal risk profiles with few to no adverse effects reported. That said, ashwagandha isn’t safe for pregnant or breastfeeding individuals, and it can stimulate thyroid activity, so anyone with thyroid concerns (hyper- or hypothyroidism) or on medication to regulate thyroid function should be careful. 36 37

Thesis also limits their formulas to a handful of ingredients, which reduces the likelihood that any one of them would cause an adverse reaction. This is pretty typical of nootropics in Thesis’ class, but less expensive nootropics might try to convince you of their value by stuffing a single blend with several dozen components. That might increase the chances you feel some positive effect, but the side effect risk goes up by the same token.

Convenience

Our convenience rating considers various aspects of a user's experience. It usually starts with the quality of a product's website design and whether or not its pages are easy to navigate. We also consider the presence of subscription systems that make reordering easier and money-back guarantees that protect your investment. A company's customer service is another vital aspect of convenience, especially if you need questions answered. The quality of an FAQ section, the availability of representatives via chat or phone call, and the responsiveness to email inquiries all play a part here.

Our convenience rating is also informed by the steps required to actually take the product. Nootropics often consist of large capsules, and doses can contain anywhere from 1-7 capsules, which is awful for anyone with difficulty taking pills. Smaller capsules, fewer capsules per dose, and simple dosing schedules are ideal. Thesis’ capsule count varies per formula, ranging from 2-4 mid-size capsules you can take 30 minutes before you might want or need their effects.

To summarize some important aspects of nootropic company convenience, let's look at which companies have large capsule counts, good money-back guarantees, and subscription systems.

Thesis also provides a service that few other companies offer: free consultations with in-house nootropic coaches. These experts can help you figure out the best time to take specific Thesis formulas and guide your experience so you can tell whether or not they're working for you. Follow-up consultations are also free as long as you subscribe to the product.

What are nootropics?

Nootropic is a term most people use to refer to any non-prescription supplement that can boost brainpower. 4 The technical definition is a little more nuanced — encompassing prescription medications like Ritalin and Adderall — but the supplement industry has largely co-opted it to categorize the new class of non-prescription products. The word loosely translates from its Greek origins to mean mind-changing, and the majority of ingredients in a given nootropic seek to alter the brain’s cognitive abilities, as well as its governance of mood and energy.

Most nootropic supplements contain botanical ingredients, vitamins, minerals, and amino acids that boast at least some clinical research connecting them with improvements in any of the following:

Compared to their prescription cousins, nootropic supplements aren't particularly strong. Still, limited clinical research indicates a tangible benefit to taking them.

What is Thesis?

Thesis is a supplement company with a focus on nootropics. Their founders each had experiences growing up with what would today be considered learning disabilities, and they credit nootropics for changing their lives. They make six distinct nootropic formulas, each with a specific ingredient profile.

Thesis differentiates themselves from their competitors in several critical ways:

• They offer a starter kit containing a personalized combination of four blends.
• You have the option to remove caffeine by request from any formula.
• They provide some of the best phone support we've ever experienced.
• Their targeted formulas conform to changing needs.

By providing you with a mix of formulas, Thesis gives you the ability to enhance the aspects of your cognitive and emotional life that need it the most on any given day. Maybe you know you have low energy levels on Mondays and Wednesdays, so you can take the Energy formula on those days. Maybe you want to devote your weekends to artistic pursuits. You can use the Creativity blend for that. Or you might find that one of their six blends works well for you in any situation. In that case, you can adjust your order to receive only that formula.

Thesis' customer service — particularly over the phone — is outstanding. While many customers might find chat support more convenient, our testers rarely waited more than a minute to speak to someone, and Thesis employs phone operators who are extraordinarily knowledgeable about the product and nootropics in general. Their email support is fine, and their chat support often redirects to an email inquiry. But that phone support is some of the best our testing team has experienced.

Is Thesis safe?

Most of the ingredients that Thesis uses in their nootropics exhibit minimal side effects in clinical research, so there’s a good chance that Thesis' various formulas will be safe for most people. But Thesis has nearly three dozen ingredients in their catalog, and not all of them will be safe for all users, including those who are pregnant or breastfeeding. Of course, the most important thing you can do is talk to your doctor before taking Thesis.

The most common side effects to watch out for when you start taking Thesis nootropics include:

• Loss of appetite
• Digestive issues

Thesis advises discontinuing their nootropics if you experience persistent headaches or an upset stomach.

Some Thesis products may present contraindications with certain prescription medicines. For example, ashwagandha has been shown to normalize thyroid hormone levels in people with hypothyroidism. 5 This has led some to believe that it could conversely cause thyrotoxicity in people with hyperthyroidism, though it’s worth noting that the study in question employed double the highest ashwagandha dose you’ll find in Thesis nootropics — the study used 600mg, and the ashwagandha dose in Thesis’ Creativity is 300mg.

Still, this should make abundantly clear the case for speaking with your doctor prior to taking Thesis. This is especially true considering the lack of research into the specific ingredient combinations you’ll find in Thesis products. There is also very little research looking into the risks of combining nootropic supplements with prescription stimulants such as Ritalin, Adderall, or Vyvanse.

Some side effects, such as jitteriness, can be attributed to the caffeine in Thesis formulas. The fact that you can elect to remove caffeine from any formula expands the company’s reach to anyone with caffeine sensitivities and those who really don’t want to give up their morning cup of coffee. If you want caffeine in your Thesis formula, we recommend trying it without having had any coffee first, so you can see how it affects you.

Insider Tip: If you’re not sure whether to get your formula with or without caffeine, we recommend getting it with caffeine. Thesis isolates the included caffeine in a single capsule separate from other ingredients. Caffeinated formulas cost the same as uncaffeinated ones, and you can always elect not to take the caffeine capsule (the smallest capsule in any formula, containing a white powder).

What are the ingredients in Thesis?

Thesis uses an impressive set of ingredients, many of which have been part of respectable clinical research. Not all of the effects they hope these ingredients provide have been proven with sufficient statistical significance or over multiple studies in different populations, but what we do know strongly suggests efficacy.

Here's a look at several Thesis ingredients that have encouraging research behind them:

Several studies on mice show that dihydrohonokiol-B (DHH-B) has potent anxiolytic effects. 6 That means it may be able to help combat anxiety. However, we can’t say this for sure since there haven’t been any studies conducted on humans yet, so any potential benefits are speculative at this time. 25 Converting the successful dose used in mice (1mg) to the equivalent human amount (4.86 mg) is about half the amount used in Thesis’ Confidence (10mg). 6

In numerous studies, ashwagandha has been shown to reduce stress and anxiety. 32 Thesis uses a branded KSM-66 ashwagandha, which has a high standardized count of withanolides — the component of ashwagandha responsible for its positive effects. 33 This ensures both efficacy and consistency from doses that align with those used in successful studies.

While every formula is different, you'll notice that each contains caffeine and L-theanine. The nootropic properties of caffeine are well established. 19 L-theanine — a non-stimulant derived from green tea — has been shown to smooth out the jittery effects of caffeine. You can easily have caffeine removed from any Thesis formula for no extra cost, which is unique in the nootropic market. The L-theanine will remain, as it has its own set of cognitive benefits in addition to its ability to tame caffeine. 20

Saffron offers multiple benefits, including increased levels of dopamine and glutamate, that are dose-dependent. Human studies have also shown positive effects on depression symptoms. Thesis’ Confidence uses 28mg, which is 2mg less than what was used in many of the studies on saffron’s antidepressant effects. However, one study did find success with as little as 15mg. 7

A review of more than 120 scientific articles looking into the cognitive effects of phosphatidylserine concluded that it “safely slows, halts, or reverses biochemical alterations and structural deterioration in nerve cells.” The study goes on to say that it “supports human cognitive functions, including the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories, the ability to retrieve memories, the ability to learn and recall information, the ability to focus attention and concentrate, the ability to reason and solve problems, language skills, and the ability to communicate.” 34

Derived from a South African plant, Zembrin appears to provide cognitive and anti-anxiety effects as demonstrated in clinical studies on human participants that used the same 25mg dose found in Thesis Creativity and Confidence. 8

Synapsa is a patented form of Bacopa extract, a traditional Ayurvedic memory enhancer. Studies on humans resulted in statistically significant improvements in cognitive tests. The study used 150mg twice daily (300mg total), which is only 20mg less than the 320mg used in Thesis’ Logic. 9

7,8 DHF is a small molecular TrkB agonist that can easily cross the blood-brain barrier. It can increase brain-derived neurotrophic factor (BDNF), a protein that improves neuroplasticity, learning, and memory. BDNF deficiencies are connected to numerous cognitive ailments as well. However, no human studies have been conducted. 26 In mice, 7,8 DHF appears to enhance spatial memory. When converting the effective dose for mice to humans, Thesis’ Clarity offers roughly 6mg more (about 24mg compared to Thesis’ 30mg). 27

Choline is a precursor to acetylcholine, a powerful neurotransmitter in the peripheral, autonomic, and enteric nervous systems. 10 One study on older adult human participants found that taking 187-399mg per day of choline reduced the risk of low cognitive functioning by nearly 50% compared to an intake under 187mg per day. 28 The CDP choline content in Thesis’ Energy is 300mg.

A 2010 clinical study on 485 older adult (over 55 years old) subjects found that 900mg per day of DHA improved memory and learning in those with age-related cognitive decline. 11 And another study in healthy adults 18-90 years old found that 580mg per day helped improve memory. 29 Unfortunately, the amounts used in many studies to improve cognitive function are quite a bit more than the 200mg (which is DHA and L-lysine combined) found in Thesis’ Logic.

Like choline, Alpha-GPC acts as an effective acetylcholine precursor. Studies also show that supplementation with Alpha-GPC can stave off exercise-induced reductions in choline levels. The effective amount used in the mentioned study is 200mg, which is less than half of what you’ll find in Thesis’ Clarity (500mg). 12

In addition to being an effective treatment for neuropathic pain, agmatine appears to have potent effects as an antidepressant. A five-year safety case report study concluded that there are no long-term side effect risks. Thesis’ Creativity only contains 250mg, which is well below the amount tolerated by study participants (2.67g per day). 13

Research into epicatechin indicates that it can enhance cerebral blood flow, delivering more oxygen to the brain to ensure it operates at its highest efficiency. The most effective dose for cognitive benefits appears to be over 50mg per day, and Thesis’ Clarity contains 278mg. 14

Lion's mane has been shown to increase nerve growth factor and promote neurite outgrowth of specific neural cells. It's a safe and reliable neurotrophic, but studies have debunked claims of neuroprotective properties. 15 A very small study of only 41 participants found that 1.8g of Lion’s mane may reduce stress and improve cognitive performance. 30 Thesis’ Clarity contains 500mg of Lion’s mane.

Hyperphenylalaninemia, a severe deficiency in phenylalanine, results in reduced dopamine, serotonin, and noradrenaline levels in the brain. 16 It can also alter cerebral myelin and protein synthesis. Supplementing with phenylalanine may provide neuroprotective benefits.

In a 2020 study, phenylalanine was a large component in a mix of seven amino acids that appeared to improve cognitive, psychological, and social functioning in middle-aged and older adults. Effective doses ranged from 0.85g to 1.7g of phenylalanine. A serving of Thesis’ Motivation contains 500mg, a bit under half of the average amount. 31

Examining the six formulas

Thesis has six nootropic formulas in their lineup (even though you can only choose up to four of them per box). Several other nootropic companies like TruBrain and BrainMD boast targeted lineups, as well, but Thesis is the Goldilocks of the bunch. Where BrainMD’s hyper-specific formulas rely on perhaps too few ingredients to make them worthwhile, many of TruBrain’s complex blends lack real specificity. With Thesis, you get targeted effects from numerous ingredients in moderately complex and reasonably priced combinations.

Each Thesis formula has a blend of ingredients that addresses specific needs. Their names give you a pretty big clue as to what the company intends each to do, but a closer look at their ingredients will help you understand how they achieve this.

Their formulas are:

Interestingly, the company thinks of its formulas as working well in pairs. You don't have to utilize them as such, but it's helpful to know how they view their most effective combinations. The following list details their purported combined benefits.

Enhances focus, eliminates brain fog, and lets thoughts flow naturally

Gets you going, keeps you going, and never crashes

Sparks new ideas, inspires extroversion, and revels in openness

You'll usually only take one formula at a time, but these pairs may act synergistically for specific personality types or cognitive needs.

Note that your first shipment of Thesis will contain six individually packed doses for four of these six formulas. Thesis chooses these formulas for you based on the results of an intake questionnaire, but you can make adjustments to that shipment on the customer dashboard before the shipment leaves their warehouse.

Let's take a closer look at each formula as they would appear with caffeine included.

Thesis Clarity

Thesis Clarity relies on 7,8 DHF (dihydroxyflavone), Alpha GPC (glycerylphosphorylcholine), epicatechin, and lion's mane to increase blood flow to the brain and stimulate the production of acetylcholine, a powerful neurotransmitter associated with learning, memory, and attention. It's particularly adept at cutting through brain fog.

Here's a look at Clarity's full ingredients list:

• Alpha GPC: 500mg
• Lion's Mane Mushroom: 500mg
• Camellia sinensis tea leaf: 278mg
• Dihydroxyflavone: 30mg
• Caffeine: 100mg
• L-Theanine: 200mg

One dose of Clarity consists of four capsules for the caffeinated formula and three capsules for the stimulant-free formula.

Thesis Logic

Thesis Logic contains triacetyluridine (TAU), which caters to the health of the entire central nervous system. It also uses phosphatidylserine to help facilitate communication between and protection of brain cells. 17

This is Logic’s complete ingredients list:

• Ginkgo Biloba: 160mg
• Theobromine: 100mg
• Phosphatidylserine: 400mg
• High DHA Algae: 200mg
• Triacetyluridine: 30mg
• Bacopa Monnieri: 320mg

One dose of Logic consists of four capsules for the caffeinated formula and three capsules for the stimulant-free formula.

Thesis Energy

Thesis Energy uses cysteine and tyrosine alongside caffeine to deliver a steady energy supply. It also includes TeaCrine, a branded form of theacrine, which partners with caffeine to affect adenosine signaling and prevent fatigue.

Here’s a full list of Energy’s ingredients:

• Citicoline: 300mg
• Mango leaf: 300mg
• Theacrine: 100mg
• N-Acetyl cysteine: 500mg
• Indian trumpet tree: 100mg
• N-Acetyl L-tyrosine: 300mg

One dose of Energy consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Motivation

Blood flow and cellular function are at the core of Thesis Motivation . It employs artichoke extract, forskolin, and B12 to achieve these goals, with a healthy dose of phenylalanine for added focus and motivation.

Here's Motivation's full ingredients list:

• L-Phenylalanine: 500mg
• Methylliberine: 100mg
• Vitamin B12: 1000mcg
• Forskolin: 250mg
• Artichoke: 450mg

One dose of Motivation consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Creativity

Thesis Creativity aims to realign you with your inspiration by removing barriers caused by stress, anxiety, and depression. It contains ingredients with powerful anxiolytic properties and 5-HT reuptake inhibition.

Here's a look at Creativity’s ingredients list:

• Alpha GPC: 150mg
• Agmatine sulfate: 250mg
• Panax ginseng: 200mg
• Ashwagandha root: 300mg
• Sceletium tortuosum : 25mg

One dose of Creativity consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Thesis Confidence

Confidence is designed to work hand-in-hand with Creativity, using saffron and DHH-B from magnolia bark to increase dopamine levels and decrease anxiety. One fascinating ingredient in this formula is sage extract, which one 2021 study showed can help with various memory tasks, including name and face recognition. 18 It’s worth noting, though, that this study employed a 600mg dose compared to Thesis’ 333mg dose.

Here is Confidence's complete ingredients list:

• Saffron: 28mg
• Magnesium bisglycinate: 500mg
• Sage: 333mg
• Magnolia Bark: 10mg
• Ashwagandha leaf & root: 120mg

One dose of Confidence consists of three capsules for the caffeinated formula and two capsules for the stimulant-free formula.

Our Thesis testing results

Our testing team has tried every Thesis formula (with and without caffeine) to determine their short- and long-term efficacy, at least at an anecdotal level. Here’s a quick summary of our experiences:

Clarity provided our testers with a combined sense of focus and mental ease, though we mostly found that it worked best from its second day forward. The very first dose is mildly effective, but it served us better as a loading dose. We had no crash from either caffeinated or uncaffeinated formulas.

Our testers found that Logic provided a similar experience as Clarity, increasing focus and mental acuity, but the caffeinated formula caused a crash in two of our testers. By excluding the caffeine, that crash can be avoided, though that comes at the expense of some efficacy.

We were very curious about how this formula would perform without the caffeine. Our testers had a noticeable increase in energy without jitteriness about one hour after taking Energy. The caffeinated version caused the worst crash of all the formulas, but we were pleased to find that the formula without caffeine still provided noticeable energy increases without a crash.

Our testers are generally a pretty motivated bunch, so we might not have been the best group to evaluate this particular formula. The testers who felt an uptick in a sense of motivation described it more like a feeling of being able to follow through on tasks with less distraction and completion anxiety.

Creativity, like Clarity, seemed to work better for our testers on its second and third days than on its first. Testers generally described a sensation similar to Motivation but without the feeling of being “on rails,” as one tester put it. It seems to allow for more curiosity and exploration, though not necessarily as much follow-through.

This is Thesis’ newest formula, so fewer of our testers have tried it. Among those who have, one tester with a mild case of social anxiety described feeling a bit more relaxed among groups of people. Testers preferred this formula without caffeine.

Thesis pricing, shipping, and returns

Thesis keeps their price structure decidedly simple. This is refreshing, considering the range of nootropics they offer. You don't have to worry about one formula costing you more than another. However, Thesis doesn't make a non-subscription approach economically feasible.

Every Thesis shipment — including the starter pack — consists of four small boxes, each containing six doses of a single formula. That’s 24 doses/month.

Here's how it works:

• Any one-time purchase of a one-month supply, including the starter kit, costs $119.
• When you subscribe, that monthly cost is only $79.
• You can take an extra 10% off your first order with the coupon code INNERBODY

Subscriptions require an account with Thesis, which gives you access to a well-designed customer dashboard. This is where you can easily make formula adjustments, alter your shipping schedule, or cancel your subscription entirely.

Shipping from Thesis is free in the U.S., and the company offers a 30-day money-back guarantee. In our testing experience, we attempted a return on a second shipment into the subscription. While it isn’t the company’s policy to do so, they refunded our money and let us keep the product. This is similar to some other “Keep it” guarantees we’ve seen from competitors, and we appreciated it.

Getting started with Thesis Nootropics

Thesis' website is easy to navigate, but it is inconvenient that you must complete the signup questionnaire before accessing formula-specific pages. There are ways around this — like direct searching or just knowing the formula URLs — but we think reviewing formulas should be a little easier when you first get to the site. And you won’t be able to place an order for anything until you complete the questionnaire.

The user interface for managing your subscription is exceptionally intuitive. You can quickly adjust your formula combinations, specifying whether or not you want specific formulas to contain caffeine.

Setting up a subscription with Thesis is a straightforward process. Here are the basic steps:

• Take the Thesis quiz . This will create a starter kit specific to your results. (You can also build a box from scratch if you know which formulas you want to try.)
• Order your starter kit. We recommend going with the kit Thesis creates after your quiz, but if you change your mind, you can use the customer portal after placing your order to make any changes to the formula combination before it ships.
• Set up a coaching consultation. This is an optional step, but we recommend it and encourage you to have your first consultation before your kit arrives.
• Take your nootropics as needed. Most people can experience some of Thesis nootropics' benefits within a few hours of ingestion. Some ingredients and formulas may take a few days to produce results.
• Refine your order. As you near the end of your first month, you can head over to the Thesis website and customize your next order to include the formula or formulas you like most.
• Set up follow-up consultations as needed. These will help you refine your future orders and maximize your results.

When you subscribe to the starter kit, you will continue receiving that kit every month until you customize your order. Thesis divides their boxes into four six-dose supplies, and you can mix and match those supplies to suit your needs. For example, you could boost energy on the weekdays and creativity on the weekends by getting a one-month supply with 18 servings of Energy in three packages and six servings of Creativity in a single package.

Personalized insights and coaching

When you take the quiz on the Thesis website, you'll get personalized insights comparing your results to other quiz-takers and a data set developed from nearly 500 scientific studies. The parameters in your results cover don’t completely line up with their formulas, but they include:

These results inform the system to make recommendations for your starter kit. After you order, you can set up a consultation with a Thesis coach. These consultations are free, and you can have as many follow-up sessions as you like. Other companies have apps or online resources like blogs or courses to help you on your nootropic journey, but Thesis’ personalized coaching offers a unique approach and execution.

Consultation calls last around 15 minutes, though some of our testers had their sessions go longer as their coaches' schedules allowed. We received best practices information about taking nootropics that covered dose timing, formula application, and more. Some of our testers also received diet and exercise advice that coincided with their formulas.

Alternatives to Thesis

There are generally two tiers of products in the nootropics landscape. The lower tier consists of products that cost between $20 and $40. Many of these nootropics contain proprietary blends that obscure the exact quantities of ingredients, presumably so companies can use more of the least expensive components. Some companies in this tier disclose their ingredient quantities but may not source them from the highest quality suppliers or perform third-party testing of any kind.

Top brands in this tier include:

• Onnit Alpha BRAIN
• Moon Juice Brain Dust
• Focus Factor

The second tier — where you'll find Thesis — consists of more expensive nootropics that spell their contents out clearly, use high-quality ingredients, and often perform third-party testing to ensure safety and potency. Top brands in this tier include:

• Qualia Mind

Hunter Focus

We have a comprehensive breakdown of our top nootropics , but here's a concise breakdown of Thesis' most comparable competition.

TruBrain offers one of the widest varieties of nootropics of any company — one of the few catalogs that rivals the variety Thesis offers. They also have some novel and beneficial delivery methods for their nootropic ingredients. Those include energy bars and liquid shots that are outstanding for anyone with difficulty swallowing pills.

TruBrain offers their nootropics in a targeted fashion, not unlike what you get from Thesis. They formerly offered their targeted blends in shot form only, but now you can get any of these targeted blends in capsule or liquid shot form. The shots come in small 1oz pouches that make them easy to take anywhere.

TruBrain's targeted blends include:

This is TruBrain's original blend. It contains seven nootropics, including Noopept, a branded form of N-phenylacetyl-L-prolylglycine ethyl ester. This blend is caffeine-free.

The Strong blend is identical to the Medium formulation in contents and doses, but it also contains 100mg of caffeine.

The Extra Strong formula builds on the Strong blend by adding 150mg of adrafinil (2-(diphenylmethyl)sulfinyl-N-hydroxyacetamide). 21 This wakefulness-promoting substance may also help with weight loss and athletic performance.

TruBrain's Sleep formula contains just four nootropic ingredients: GABA, melatonin, 5-HTP, and a blend that TruBrain calls "functional oils."

Mellow is identical to the medium strength formula, but it adds the functional oil combination used in Sleep.

This formula contains Lion's mane, a mushroom that may promote neural growth , though human studies are necessary to determine if this is true. 22 Its other nootropic ingredients are rhodiola, guayusa, and rosehips.

A 30-day supply of TruBrain nootropic shots costs $89. That's $10 more than the subscription cost for a one-month supply of Thesis. Some of their shots contain caffeine, and others don't. If it already contains caffeine, there's no way to alter a TruBrain formula to be stimulant-free.

The first month of TruBrain capsules costs a bit less, coming in at $69. After your first month, however, the price goes up to $119. That makes Thesis the better value, but if you want the best possible nootropics for sleep support, it might be worth the extra money to check out TruBrain.

Qualia Mind is a brand under the Neurohacker Collective, a company that offers several products to address things like sleep quality, skin health, and vision. They have three nootropics available:

• Qualia Mind Caffeine-Free
• Qualia Mind Focus

Their original blend is comprehensive, consisting of nearly 30 ingredients in high doses. That means it's liable to provide you with noticeable effects. It also means you might not know which of those effects are coming from which ingredients, and some of the less beneficial components in your body may also have side effects you'd rather avoid.

The caffeine-free version is identical to the original formula but leaves the caffeine out. Qualia Focus is a more streamlined offering with only seven nootropic ingredients, including caffeine, L-theanine, and L-ornithine. 23

Initial shipments from Qualia Mind are significantly discounted, but after the first month, the price makes theirs one of the most expensive nootropics we've tested. For example, the first month of a subscription to Qualia Mind costs just $39. After that, it costs $139/month. And a one-time purchase is $159.

One inconvenient aspect of Qualia Mind is that a single dose consists of seven capsules, which can get tiresome even for people who don't have trouble swallowing pills. On the bright side, Qualia's 100-day money-back guarantee allows you to try it for a little over three months to determine if you can handle that kind of daily dosing.

Hunter Focus is one of three supplements in the Hunter stack alongside the company's Test and Burn supplements. The stack is intended for male use — Test is a testosterone supplement — but Focus and Burn are suitable for men and women.

Like Qualia Mind, Focus has a long list of ingredients in generous doses. In fact, one serving of Hunter Focus is like taking all six of Thesis' formulas at once. That said, the serving itself is difficult to swallow, as it consists of six large pills.

Another knock on Hunter is that they don't offer a subscription system. That means you can't get an extra discount, and you must remember to reorder when you're running low (theoretically, a nootropic like this should boost your memory). There's also no money-back guarantee to speak of, only a return policy with a relatively short window that only applies to unopened products.

One bottle of Hunter Focus costs $90, and shipping is $8.95 unless you buy more than one bottle at a time. The company will throw a fourth in for free if you buy three bottles at once. That's the only way to get any savings through Hunter.

Individual nootropic components

Many companies offer combinations of nootropic ingredients to perform specific brain-related tasks or even provide globally positive cognitive benefits. However, the scientific research behind most of these ingredients almost always includes just one rather than a combination. Some people prefer to try one at a time to minimize the potential for side effects and determine if one particular ingredient works for them. A few companies offer single-ingredient nootropic supplements for this specific purpose.

Our favorite company dealing in individual nootropic components is Nootropics Depot. They offer a wide variety of single-ingredient supplements and a few targeted blends. The prices are generally fair, with an average range running from $16-$70. A 30-day money-back guarantee covers every purchase, and you get free shipping on orders over $50.

Nootropics FAQ

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Specific nootropics affect different parts of the brain in their own ways. Some — like caffeine — reduce fatigue by blocking adenosine receptors, while others act to protect neural connections that are already present while possibly contributing to new neural growth. 24 Some also mitigate depression and anxiety, which frees up the brain to perform at its best.

Are nootropics safe?

The safety of a nootropic depends on the specific ingredients involved. Many are perfectly safe in the doses commonly employed by nootropic companies, but some can cause reactions like increased heart rate, gastrointestinal discomfort, headache, and even tremors. The smartest thing to do is to talk to your doctor before introducing any new supplement to your regimen.

Do nootropics really work?

Many nootropic supplements are noticeably effective — caffeine is a great example. Efficacy varies depending on the specific component or combination. Fortunately, a lot of companies offer money-back guarantees, so you can try their products to see if they work for you without much financial risk.

Will nootropics make me smarter?

Nootropics won't necessarily make you smarter, but many can increase your alertness, improve short-term recall, and promote neural growth and protection. That creates a great environment for learning if you apply yourself while using nootropics, and many ingredients can help you with the motivation it takes to do so.

How do you pronounce nootropics?

The 'noo' in nootropics comes from the Greek nous , which philosophers use to mean mind or intelligence. The 'tropic' in nootropic comes from the Greek tropikos , which relates to turning or changing. So, nootropic roughly translates to mind-changing. You pronounce the 'noo' like 'new' and the 'tropic' with a long O sound, like 'toe pick.'

Innerbody uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

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I Tried Thesis Nootropics—Here’s My Honest Review

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Table of Contents

Our verdict, thesis nootropics at a glance, how does thesis nootropics work, how much does thesis nootropics cost, the product, my thesis nootropics experience, what experts say about thesis nootropics.

Thesis nootropic blends, which are nutritional compounds often used to boost brain function , are designed to enhance mood and cognitive performance based on your individual needs and goals. The Starter Kit allows users to sample four of Thesis’ nootropics blends to determine which is most effective for them.

While the supplements are pricey, I found the increased productivity and enhanced focus I experienced worth the cost.

• Supports memory, focus, and mental speed
• Helps optimize cognitive function
• Caffeine-free and gluten-free formula
• Sold over 10 million bottles
• Subscribe and you’ll save up to 35% off

Key Features

• Thesis nootropics are designed to enhance cognitive function and optimize brain performance by supporting mood, memory, focus, cognitive processing, creativity and motivation, according to the company.
• Ingredients and blends are third-party tested for quality and potency by an independent lab, according to the company.
• Products are backed by a 30-day money-back guarantee (with a maximum return limit of a one-month supply).

Dan Freed founded Thesis in 2017 after finding inspiration from his personal journey with nootropics. With company headquarters in New York, Thesis offers customized nootropics to support cognitive function and boost productivity.

• Thesis nootropics are sourced from vegan ingredients like saffron, ginkgo biloba, mango leaf and lion’s mane mushrooms that have been studied for their impact on mood and cognitive function.
• A Thesis Starter Kit costs $119; monthly subscriptions are available for $79.
• With the Thesis Starter Kit, you can try four of the six available blends—Motivation, Clarity, Creativity, Energy, Logic and Confidence—for six days each to determine which blend works best for your brain chemistry.

Thesis nootropics are designed to enhance specific elements of brain health, from focus to energy. To get started with Thesis, you can take an online survey or choose your own blends.

If you choose to complete the online quiz (the option recommended by Thesis), you’ll answer questions about the following:

• Your age, weight and identifying gender
• Areas you’d like to focus on, such as energy, motivation or mood
• How much caffeine you drink and how it affects you
• How often you exercise
• Whether you consume excess alcohol (five or more  drinks per day)
• Whether you smoke or vape
• How much sleep you get nightly
• How often you forget things

You’ll also rate your energy, sleep quality, productivity, focus, mood and anxiety levels. Once you finish the quiz, suggested blends based on your specific needs and goals are populated for purchase on the website. You can choose to purchase a one-time or monthly package.

Each Thesis Starter Kit contains four boxes of nootropic blends, each containing six sachets of capsules. Users can try  four recommended blends from the six available through Thesis. Capsules are taken first thing in the morning (on an empty stomach) for six consecutive days, followed by a one-day break to gauge  each blend’s results. You’re encouraged to write down how you feel, including any benefits and side effects you notice.

Customers have free and unlimited virtual access to wellness coaches. Sessions are 15 minutes each and must be scheduled in advance. During your first session, your coach  guides you through each customized blend, goes over the instructions and answers any questions you may have. If there’s a blend that’s not working for you, Thesis coaches can help you make adjustments to your plan.

Monthly subscriptions can be managed in your online profile, so you can choose which blends you’d like to receive after the initial period.

• Contains 1000mg of Organic Lion's Mane in every serving
• Formulated with organic reishi, lion’s mane, and Cordyceps sinensis
• Packed with bioactive constituents that promote overall health and longevity
• Informed Choice Certified for dosage, purity, and safety from banned substances

The Thesis Starter Kit is available on the company’s website for $119. Customers can also sign up for a monthly subscription plan for $79 (a discount of $40). Shipping is free.

My curated sampler kit, based on my survey results, contained the following blends.

This blend contains four capsules and is formulated to promote energy, fight fatigue and increase mental stamina. The key ingredient theacrine, which is a naturally-occurring compound found in plants, has been shown to improve energy levels, motivation and concentration, the company notes. It also contains N-acetyl cysteine (NAC), which research suggests possesses  promise as a supplement for cognitive function. However, clinical trials studying the effects of these two particular ingredients are inconclusive, and more research is needed.

That said, a large body of research supports the combination of caffeine and L-theanine (also contained in the Energy blend) for increased energy and attention, says Umo Callins, a board-certified sports dietitian and fitness coach at Well Rooted Health and Nutrition in Oklahoma City.

Active ingredients of the Energy blend include:

• Citicoline: 300 milligrams
• Mango leaf extract: 300 milligrams
• Indian trumpet leaf extract: 100 milligrams
• Theacrine: 100 milligrams
• N-acetyl L-tyrosine: 300 milligrams
• N-acetyl cysteine: 500 milligrams
• Caffeine: 100 milligrams
• L-theanine: 200 milligrams

This four-capsule blend is designed to spark imagination, maintain confidence and support verbal fluency, according to the company. The focus ingredient, ashwagandha, has been shown to reduce stress and anxiety in clinical trials. The blend also contains L-theanine, which may have relaxing effects, acting as a buffer for stress and anxiety.

Active ingredients of Creativity include:

• Ashwagandha root: 300 milligrams
• Panax ginseng: 200 milligrams
• Sceletium tortuosum: 25 milligrams
• Agmatine sulfate: 250 milligrams
• Alpha GPC: 150 milligrams

This blend, containing three capsules, is designed to help maintain willpower, prevent procrastination and manage stress, notes the company. The featured ingredient, CDT (Dynamine)—which is a patented, standardized form of methylliberine, a compound found in plants—may assist with cognitive control and improve reaction time during mentally challenging tasks, the company claims, but supporting research is limited.

Because the blend also contains caffeine and L-theanine, Callins says it will likely help with productivity, especially in a stressed or anxious state.

Active ingredients of Motivation include:

• Artichoke extract: 450 milligrams
• Vitamin B12 : 1,000 micrograms
• L-phenylalanine: 500 milligrams
• CDT (Dynamine): 100 milligrams
• Forskolin: 250 milligrams

Thesis claims that this three-capsule blend is designed to maintain focus, support attention and help individuals enter a flow state. According to the company, the featured ingredient, alpha-GPC, a compound found in the brain and in trace amounts in food sources like egg yolks and organ meats, supports healthy cognitive function and physical performance, but supporting research is limited. The blend also contains caffeine and L-theanine, which can help boost focus and attention, says Callins.

Active ingredients of Clarity include:

• Alpha-GPC: 500 milligrams
• Lion’s mane mushroom: 500 milligrams
• Camellia sinensis tea leaf: 278 milligrams
• Dihydroxyflavone: 30 milligrams

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The customized blends I received from Thesis were Energy, Clarity, Creativity and Motivation. For each blend, I followed the instructions as indicated, taking the supplements in the morning on an empty stomach (with a glass of water). I took each blend for six consecutive days, followed by a one-day break.

I didn’t notice much of a difference from my baseline mood or energy from the Creativity blend, and the Motivation blend gave me heartburn, so I stopped using it after a few days. According to Thesis, experiencing negative side effects is a sign the specific blend is not a fit, and you should move on to the next one. When I took the Energy blend before my morning workout, I experienced a mild boost to my mental and physical stamina.

Hands down, my favorite blend was Clarity. I was amazed by how big of an impact this nootropic blend had on my focus, attention and productivity. As someone with inattentive ADHD (a type of attention-deficit/hyperactivity disorder that manifests as distractibility and forgetfulness), tasks requiring sustained attention can be challenging. Clarity’s effects were noticeable immediately (within 30 minutes), and I had an incredible level of focus that lasted. I don’t take ADHD medication because it interferes with my sleep, so this was an exciting find.

I was pleasantly surprised by the effectiveness of Thesis nootropics. For me, Clarity was the most effective blend, but I enjoyed experimenting with different formulas. While it’s pricey, I’ll definitely use Thesis again, thanks to the huge improvement in focus and attention I experienced.

Nootropics, also referred to as cognitive enhancers or “smart drugs,” are natural or pharmaceutical substances used to boost brain activity and cognitive function, explains Callins. Potential benefits include improved memory, focus, thinking, learning and mood management, she says.

Although many nootropics are generally considered safe, Callins says consuming more than the recommended dose can result in mild side effects like dizziness, nausea and headaches. And while some of the ingredients in Thesis products may have cognitive benefits supported by research, she points out that more data on their long-term effects and safety is needed.

The bottom line? “Always consult with your doctor or primary health care practitioner before taking any supplement,” advises Callins, adding that some nootropics are contraindicated with certain medical conditions and medications.

• Kuhman DJ, Joyner KJ, Bloomer RJ. Cognitive Performance and Mood Following Ingestion of a Theacrine-Containing Dietary Supplement, Caffeine, or Placebo by Young Men and Women. Nutrients. 2015;7(11):9618-32.
• Skvarc DR, Dean OM, et al. The effect of N-acetylcysteine (NAC) on human cognition - A systematic review. Neurosci Biobehav Rev. 2017;78:44-56.
• Anas Sohail A, Ortiz F, et al. The Cognitive-Enhancing Outcomes of Caffeine and L-theanine: A Systematic Review. Cureus. 2021;13(12):e20828.
• Ashwagandha: Is it helpful for stress, anxiety, or sleep?. National Institutes of Health. Accessed 2/28/23.
• Wang L, Brennan M. How does the tea L-theanine buffer stress and anxiety. ? Food Science and Human Wellness. 2022;11(3):467-475.
• La Monica MB, Raub B, et al. Methylliberine Ingestion Improves Various Indices of Affect but Not Cognitive Function in Healthy Men and Women. Nutrients. 2023;15(21):4509.
• Parker AG, Byars A, et al. The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility. J Int Soc Sports Nutr. 2015;12(Suppl 1):P41.
• Tamura Y, Takata K, et al. Alpha-Glycerylphosphorylcholine Increases Motivation in Healthy Volunteers: A Single-Blind, Randomized, Placebo-Controlled Human Study. Nutrients. 2021;13(6):2091.
• Malík M, Tlustoš P. Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs. Nutrients. 2022;14(16):3367.
• Epstein JN, Loren RE. Changes in the Definition of ADHD in DSM-5: Subtle but Important. Neuropsychiatry (London). 2013;3(5):455-458.
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Heidi Borst is a freelance journalist, healthcare content writer and certified nutrition coach with a love of all things health and wellness. Her work has appeared in The New York Times, The Washington Post, National Geographic, Good Housekeeping, MSN, Yahoo and more. Based in Wilmington, North Carolina, Borst is a lifelong runner and general fitness enthusiast who is passionate about the physical and mental benefits of sleep and self-care.

Sarah is an experienced writer and editor enthusiastic about helping readers live their healthiest and happiest lives. Before joining Forbes Health, Sarah worked as a writer for various digital publications including LendingTree, theSkimm, CNBC and Bankrate. When she isn’t writing or editing, you can find Sarah with her nose in a book or enjoying the outdoors with her French bulldog, Honey.

Thesis Nootropics Helped Me Ditch My 3-Coffee-A-Day Habit

Here's what to know about the personalized supplement brand.

As someone who pours herself a tall glass of iced coffee three times a day — and sometimes even more, oops — I figured it wouldn’t hurt to look into other ways to boost my energy and focus. Of course, I also try to get enough sleep, water, and exercise, too. But I was also down to try a few supplements from Thesis, a nootropics company that aims to make you feel more productive with its plant-based blends.

If you’re not familiar, nootropics are similar to adaptogens in that they’re a class of functional plants that are buzzy in the wellness world. But nootropics — which include ingredients like ashwagandha , L-theanine , choline , and functional mushrooms — are more focused on activating different parts of your brain to support motivation, mood, memory, and cognitive processing . That’s why they’re sometimes called smart drugs or cognitive enhancers — and thus have a different role to play than everyday vitamins.

At Thesis, you’re hooked up with a kit of personalized vitamins , adaptogens , and nootropics that are meant to help support you in accomplishing your goals and feeling more energized and productive. I tried them out for a month and I have some thoughts. Here’s what it was like to try Thesis, in case you’re also a coffee fiend who could use a little more focus and energy.

• Price: $79/monthly subscription
• Best for: Energy, focus
• My rating: 4/5
• What we like: Personalized supplements, supportive coaches
• What we don't like: Can seem pricey, you have to be ready for some trial and error

What Is Thesis?

To get started, you’ll first take a quiz on the Thesis website that asks you about how you feel on a day-to-day basis, how much coffee you drink, what your energy levels are like, and how much you sleep (among other lifestyle questions) so that it can determine the best supplements for you. It’ll then send you a starter kit with six different supplement blends targeted for each issue you might be experiencing. From there, it’s up to you to decide which ones you want to continue using. It works like a process of elimination — you experiment by taking each supplement for six days to see whether or not it feels effective.

The Thesis line features eight different supplement blends: Creativity, Focus, Motivation, Clarity, Energy, Motivation, Confidence, and Logic. Though the brand notes it would love to formulate one pill that works for everyone, brain chemistry is so complex, so it decided it’s better to take the long route and have customers try multiple supplements in order to find the best fit for their noggin. That’s why Thesis also puts you in contact with a wellness coach, so you can chat and ask questions with an expert along the way.

How Do Nootropics Work?

Nootropics are meant to allow your brain to do its thing, only faster and with more efficiency. So, instead of slogging away at your desk with brain fog , you might notice that you feel perkier, extra organized, and more on-point than you normally do as you continue taking the supplements.

Some of the blends contain the nootropic acetylcholine , which is a neurotransmitter from the essential nutrient choline known for memory, learning, and healthy brain function . There are also plenty of amino acids, vitamins, and plant-based adaptogens in each packet to fight off fatigue and stress while protecting your brain from toxins so it’s easier to take in info — and actually remember what you learned. Other staple nootropics include ginkgo biloba , certain kinds of mushrooms, and caffeine, each of which plays a unique function in your cognitive function.

My Experience

When I took the Thesis quiz , I said that I wanted to improve my energy, focus, and mood. A few days later, I received my starter kit, which contained Clarity , Confidence , Motivation , and Logic all laid out in cute little boxes. You’re supposed to pick one — each box contains six sachets full of pills — and take a packet a day for six days. I was immediately drawn to Clarity, a supplement combo that’s supposed to help with high-pressure situations, concentration, and tasks that require focus and attention. It has Lion’s Mane extract (a mushroom), caffeine, L-theanine , and a few other ingredients meant to support a calm, focused flow. The idea is to take the supplements in the morning so they kick in before you start your day, and most of the effects are said to last from four to six hours.

I’d been taking Clarity for a few days when I had a phone call with Cindy Yan , a Thesis wellness coach and nootropics expert. We chatted about my usual routine, how I’d been feeling, and any questions I had about the process. When I said I felt a slight uptick in focus, but nothing too dramatic, Yan told me the first couple days are called the “loading phase” which is when the nutrients work their way into your body. If you don’t feel anything after that point, it’s a sign the supplement isn’t necessary or right for your neurochemistry. If you do like how you feel, it’s a keeper.

As we chatted about my routine, Yan realized I’d benefit from Creativity, an ashwagandha-based supplement meant for brainstorming and public speaking, so that I could feel like a rockstar at work. I also told her that I tend to crave a nap around 3 p.m., so she suggested the Energy supplement made with choline and mango leaf extract , which you can take every day or on extra-busy days, before a workout , or whenever you want to feel alert.

Talking to a coach as I tested the supplements was a true perk. While the quiz got me started with some great options, having access to Yan helped me hone in on what I truly needed.

Yan suggested I log how I felt every day as I took each supplement so I could keep track of any noticeable differences. A week in, I looked at the scribbles in my notebook and noticed that I did seem more productive during the six days I took Clarity. I wasn’t launching rockets to the moon, but I was getting through my emails and typing away like a woman on fire.

The next supplement on my agenda was Energy, a blend meant for busy days, intense workouts, and staying alert thanks to its mango leaf, theacrine , caffeine, and n-acetyl cysteine — and this is the one that gave me the most benefit. Yan was right on the money. She said I could take it in the morning and/or right after lunch to nip my afternoon slump in the bud, and it truly worked — no fourth mid-day coffee for me.

The more I took Energy, the less I felt like I needed to unhinge my jaw and dump as much cold brew into my face as possible. I found myself drinking a sensible cup or two in the morning, and that was that. Thesis says you can feel the effects of the supplements in as little as 30 minutes or it can take up to five days for all the benefits to sink in as your body and brain adjust. For me, though, Energy kicked in pretty quickly.

The Bottom Line

Typically, Thesis users land on two or three supplements for their regimen. After the month-long trial phase, you can order just the ones you want and forget about the rest. Personally, I’m sold on Energy and can see myself hanging onto Clarity, too.

Thesis seems to have figured things out in the nootropic supplement realm. While the boxes seem pricey, it isn’t so bad when you think about buying each supplement on your own individually — and the fact that you get a wellness coach, too.

TL;DR: I’d recommend it for anyone who feels fatigued, unproductive, or unfocused, or for folks who rely on caffeine to get through the day, like me. You might just find that there’s a better way.

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Gelabert-Rebato, M. (2019). A Single Dose of The Mango Leaf Extract Zynamite ® in Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women. Nutrients. 2019 Oct 28;11(11):2592. doi: 10.3390/nu11112592.

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Suliman, NA. (2016). Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic. Evid Based Complement Alternat Med. doi: 10.1155/2016/4391375.

Todorova, V. (2021). Plant Adaptogens-History and Future Perspectives. Nutrients. doi: 10.3390/nu13082861.

Wiedeman, AM. (2018). Dietary Choline Intake: Current State of Knowledge Across the Life Cycle. Nutrients. doi: 10.3390/nu10101513.

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Thesis stands out in the wellness industry with its personalized nootropic supplements, designed to cater to the individual’s specific cognitive needs. Health and wellness celebrities have pushed it, causing a wave of popularity.

Do Thesis nootropics live up to the hype?

• Variety Of Blends: Various nootropic blends based on individual brain chemistry, maximizing effectiveness for each user.
• Strong Advocacy and Support: Gained endorsements from notable wellness advocates and public figures, like Andrew Huberman, enhancing credibility.
• Limited Clinical Research: While the company plans clinical trials, the current scientific backing may be limited.
• Price: The ongoing cost of customized nootropics may be higher than standard off-the-shelf supplements or medications.
• Dependence on Self-Reporting: The effectiveness of blends relies partly on user feedback, which may not always be accurate or consistent.
• Many Underdosed Ingredients: As you’ll read below, many ingredients are dosed below what was used in human clinical trials.

Quick Verdict

Thesis has a range of suitable nootropic blends to cater to many needs.

However, our #1 nootropic of choice is NooCube. It’s designed for long-term brain changes, not just short-term boosts in mental performance.

What Is Thesis Nootropics?

Thesis Nootropics is a company that specializes in customized cognitive performance products. Dan Freed founded it in 2017.

Freed’s personal challenges with focusing, which he faced from a young age, led him to discover nootropics.

This personal journey of transformation through nootropics inspired him to create Thesis, aiming to help others find the right combination of nootropic ingredients that work for them.

The company’s unique approach involves allowing customers to experiment with high-quality nootropic ingredients to maximize results systematically.

Thesis has gained popularity primarily through word-of-mouth and a strong focus on personalization.

The company has raised over $13.5 million in funding and is reportedly profitable with a robust growth trajectory.

Thesis has garnered support from health and wellness advocates like Dr. Andrew Huberman, Rich Roll, Kevin Love, and Kate Bock.

Thesis Nootropics

Customized Blends For Cognitive Enhancement

Take the quiz and see which blends are right for you.

Thesis Nootropic Ingredients

Thesis have six unique blends designed to target various aspects of cognitive function. What’s similar between them is the option to include or exclude caffeine and L-theanine. The caffeine and l-theanine combination is the most potent instant nootropic, making each blend effective.

The caffeine L-theanine stack benefits physical and cognitive function. Some advantages include faster reaction time, faster visual processing speed, better working memory, increased awareness, and less tiredness and mental fatigue [1] [2] .

The research employs a 2:1 L-theanine to caffeine ratio, which Thesis has followed. Since this stack is available in every blend, I won’t include it in the ingredients breakdown below.

Thesis Clarity Blend

Alpha gpc (speculative).

Alpha GPC, a choline-containing phospholipid, improves cognitive function in neurological conditions like dementia [3] .

Research indicates it enhances memory and attention and may support brain health. Clinical trials show it can improve cognitive performance, especially when combined with other treatments like donepezil [4] .

It’s generally well-tolerated and safe. Alpha GPC increases acetylcholine levels in the brain, which is essential for memory and learning [5] .

It’s used both as a medicine and a nutritional supplement. Studies suggest Alpha GPC effectively boosts cognitive functions, particularly in adult-onset dementia disorders [6] .

Thesis Clarity Blend contains 500 mg, which is more than any other nootropic available.

Lions Mane Mushroom (Speculative)

The Lion’s Mane mushroom (Hericium erinaceus) includes chemicals that stimulate nerve growth factor (NGF) synthesis, which is necessary for nerve cell proliferation and differentiation [7] .

According to research, Lion’s Mane improves cognitive abilities, particularly memory and brain cell regeneration [8] .

It is renowned for its neuroprotective qualities, which may be effective in treating illnesses such as Alzheimer’s disease and cognitive impairment [9] .

Brain functioning, memory, and mood improvements have been linked to regular ingestion [10] .

While the mushroom does not directly improve cognitive skills, it does increase NGF, which improves brain health [11] . The dosage varies but is generally well-tolerated and has few negative effects.

Thesis Clarity contains 500 mg of Lions Mane, which may give a long-term nootropic effect.

Mycelium is typically avoided since the active chemicals are found in the primary mushroom. Jeff Chilton, a long-time mushroom researcher, discusses this in the podcast below:

Camellia Sinensis Tea Leaf (Speculative)

Camellia Sinensis, commonly known as tea, exhibits varying neuropharmacological effects based on the part of the plant used.

Seed extracts tend to be more stimulating, enhancing motor functions and showing potential as an antidepressant without causing drowsiness.

Leaf extracts, on the other hand, tend to produce a calming effect on the mind and mood. Both seeds and leaves have shown positive results in various tests assessing motor function and behavior in animal models [12] .

The study suggests these parts of the Camellia Sinensis plant have potential as cognitive enhancers, warranting further research, especially on seed extracts for their mode of action and possible new beneficial compounds.

I couldn’t find any human studies for this ingredient, so I can’t give you an efficacious dose range. But Thesis Clarity contains 278 mg of Camellia Sinensis Tea Leaf.

Dihydroxyflavone

Dihydroxyflavone research is all performed in rodents, so extrapolating to humans is rather challenging. 7,8-Dihydroxyflavone (7,8-DHF) is a compound that acts as an agonist for the TrkB receptor, which is associated with brain-derived neurotrophic factor (BDNF).

BDNF is crucial for neuronal survival and brain plasticity. Studies have shown that 7,8-DHF can improve memory and cognitive functions [13] .

It enhanced memory formation in healthy rats and improved spatial memory in Alzheimer’s disease mouse models [14] .

Further, 7,8-DHF has been shown to counteract aging-related cognitive impairments in rats, improving spatial memory and synaptic plasticity in the hippocampus [15] .

This suggests that 7,8-DHF is a potential therapeutic agent for memory impairment and dementia, at least in rodents.

Thesis Energy Blend Ingredients

Citicoline is commonly mentioned in relation to memory enhancement. Studies have shown that 500 mg daily may improve episodic memory or the ability to recall personal experiences and specific events [16] .

According to other research, taking at least 500 mg of this supplement daily may provide cognitive benefits to healthy persons [17] .

The formulation of Thesis Energy Blend contains 300 mg of Citicoline. This dose may not achieve the full potential seen in studies proposing a higher dose.

Mango leaf extract, rich in the polyphenolic compound mangiferin, shows promise in neuropharmacology due to its anti-inflammatory, antioxidant, and antidiabetic properties.

Studies indicate its potential in treating central complications associated with metabolic disorders like type 2 diabetes, which are risk factors for Alzheimer’s disease and vascular dementia [18] .

In animal models, mango leaf extract has demonstrated effects on reducing brain inflammation and spontaneous bleeding and improving cognitive functions [19] .

These findings suggest its utility in addressing symptoms of neurodegenerative diseases and cognitive impairments [20] .

Thesis Energy contains 300 mg of mango leaf.

Theacrine is a purine alkaloid similar to caffeine. It is found in the Camellia kucha plant and is often included in dietary supplements.

Studies show that it can increase energy, focus, and cognitive performance, similar to caffeine, but without habituation [21] .

Theacrine’s impact on cognitive performance and physical endurance has been researched in athletes, indicating possible benefits in reaction time and endurance [22] .

It may enhance cognitive function and physical performance, either alone or in combination with caffeine [23] .

Theacrine appears to be a promising supplement for improving mental alertness and physical capacity. Theacrine manufacturers fund some of these studies.

Thesis Energy contains 100 mg of Theacrine, which tends to be less than the dose used in these studies, suggesting it may have a weaker effect.

N-Acetyl Cysteine

N-acetyl cysteine (NAC) is explored for its potential to improve cognitive functions in psychosis and bipolar disorder due to its antioxidant, neurogenesis, and anti-inflammatory properties.

Studies show N-acetyl cysteine can improve working memory in psychosis [24] . However, results in bipolar disorder didn’t show significant cognitive improvements [25] .

Research indicates potential benefits for Alzheimer’s disease by promoting cognitive health and countering oxidative stress [26] .

To confirm its benefits, the effectiveness of N-acetyl cysteine in various cognitive disorders still requires more targeted, larger studies [27] .

N-acetyl cysteine’s role is promising but not yet firmly established in cognitive enhancement.

In human trials, a 600 – 2000 mg dose seems needed for cognitive benefits. Thesis Energy contains 500 mg, which is potentially underdosed.

Indian Trumpet Tree

Indian Trumpet Tree is known as Oroxylum indicum. In a 12-week study, older adults with memory complaints took 500 mg of Oroxylum indicum extract twice daily [28] .

Compared to a placebo, this supplementation improved episodic memory and numeric working memory. It also accelerated learning in location tasks.

However, there were no significant changes in other cognitive tests or overall cognitive and memory skills.

The study suggests that Oroxylum indicum, while well-tolerated, may primarily enhance specific memory functions.

Its potential effects could be linked to its antioxidant and anti-inflammatory properties and interactions with neurotransmitters like dopamine and GABA.

This is the only human study on the Indian Trumpet Tree, so more research is needed to fully understand its impact on cognitive health. Thesis Energy only contains 100 mg of this, making it potentially underdosed.

L-tyrosine, an amino acid, has been shown to increase dopamine levels in the brain. L-tyrosine supplementation has improved cognitive regulation, particularly in mentally demanding settings [29] .

It is especially helpful in improving cognitive flexibility, which is impacted by dopamine.

While L-Tyrosine’s promise for treating clinical problems and improving physical activity is limited, it is useful in stressful or cognitively taxing situations.

It has the greatest cognitive benefits when neurotransmitter activity is intact, but dopamine and norepinephrine levels are momentarily decreased [30] .

According to research, optimal doses for cognitive improvement begin at a minimum of 2 grams. That is more than six times the dose in Thesis Energy.

Thesis Creativity Blend Ingredients

Thesis Creativity contains 150 mg of Alpha GPC, yet their Clarity Blend contains 500 mg. I’m not sure why there is a large discrepancy, especially when 500 mg is likely a more efficacious dose.

Agmatine Sulfate

Currently, agmatine sulfate has only been tested in rodents. It is a central nervous system (CNS) neurotransmitter/neuromodulator that has been studied for its potential effects on stress-related conditions like depression, anxiety, and cognitive performance.

Research suggests that agmatine can have antidepressant and anxiolytic (anxiety-reducing) effects, possibly related to its influence on the nitric oxide pathway [31] .

It may reduce oxidative stress and corticosterone levels while increasing brain-derived neurotrophic factor (BDNF), which is beneficial for brain health.

In animal studies, agmatine sulfate has been shown to be safe and well-tolerated, with oral administration effectively increasing its levels in the brain [32] .

This indicates potential for therapeutic use in neurological disorders, though more research is needed to fully understand its effects and mechanisms.

Thesis Creativity contains 250 mg. In these studies, patients were administered 15-600 mg per kg, which is a much higher dose.

Panax Ginseng

Panax ginseng is available in two varieties: white ginseng and red ginseng. It has vasorelaxant and moderately hypotensive effects on nitric oxide generation in the body [33] .

It increases antioxidant enzyme activity and may prevent oxidative damage associated with aging in rats [34] .

Ginseng has shown promise in boosting memory, particularly in age-related cognitive decline, as well as in improving mental and physical resilience, reducing fatigue, and assisting the body in adapting to stress [35] .

Daily doses of 200 mg extract or 0.5 to 2 g dry root are recommended. It is not suggested for persons with acute asthma or hypertension because it may cause overstimulation and elevate blood pressure in excessive dosages.

Thesis Creativity has an effective dose of 200 mg, which may provide you with these mental performance benefits.

Ashwagandha Root

Ashwagandha is a traditional herbal remedy used to improve various health conditions. Animal studies have shown that it can increase blood cell counts, which might enhance aerobic capacity [36] .

It also demonstrates the potential to reduce oxidative stress and lipid peroxidation, which could be beneficial in treating disorders like tardive dyskinesia [37] .

Additionally, Ashwagandha has shown nootropic effects and might be useful in treating Alzheimer’s disease [38] . Recommended dosages range from 6 to 10 grams of ground roots or 100 to 1250 mg of extract daily [39] [40] .

It’s generally safe but should be used cautiously, especially in cases of hyperthyroidism or pregnancy. High doses can have sedative effects and may cause gastrointestinal issues.

Thesis Creativity contains 300 mg of Ashwagandha, which is within the recommended range for cognitive benefits.

Sceletium Tortuosum

Sceletium tortuosum, also known as Kanna, is traditionally used for its mood-enhancing properties. It’s been studied for its potential in treating cognitive and neurodegenerative disorders like Alzheimer’s and Parkinson’s [41] .

Research suggests its constituents could target enzymes and receptors relevant to these diseases, offering neuroprotective benefits like antioxidant activity [42] .

Additionally, Sceletium Tortuosum is known for its antidepressant and anxiolytic effects, promoting relaxation and well-being, which could be beneficial in managing stress, anxiety, and depression [43] .

The plant’s bioactive alkaloids are also being explored for commercial medicinal use.

The 25 mg dose in Thesis Creativity is the same as used within the human trials.

Thesis Motivation Blend Ingredients

L-phenylalanine.

L-phenylalanine is a vital amino acid and has been explored for its potential benefits in managing conditions like attention deficit disorder and depression.

Studies have shown that doses of up to 1200 mg show initial improvements in mood and attention in individuals with attention deficit disorder, but tolerance develops over 2-4 months [44] .

In another study involving depressed patients, a dosage range of 75–200 mg/day for 20 days led to significant improvements in 12 out of 20 patients [45] .

However, the effectiveness and safety of L-phenylalanine can vary, and it is used in the treatment of various conditions, including depression and arthritis, and even as part of addiction recovery [46] .

Thesis Motivation has a 500 mg dose, which may provide some of these benefits. Will it improve motivation? I’m not sure.

Methylliberine

Methylliberine is a purine alkaloid explored for its cognitive and mood-enhancing effects. Studies have shown it can improve concentration, motivation, and mood, especially when combined with caffeine.

Methylliberine also appears to positively affect energy levels and well-being without significantly impacting vital signs like heart rate and blood pressure [47] .

These findings suggest its potential as a nootropic supplement, particularly for enhancing cognitive function and mood in various contexts, such as gaming or in tactical scenarios [48] [49] .

However, it’s essential to consider the dosage and combination with other compounds like caffeine for optimal effects.

The 100 mg dose in Thesis Motivation aligns with the current research.

Vitamin B12 (Speculative)

Vitamin B12 is essential for cognitive health and may be linked to neurodegenerative diseases like Alzheimer’s and Parkinson’s.

Low levels of B12 are associated with cognitive impairment, but supplementation is only shown to be effective in improving cognition in cases of existing B12 deficiency [50] .

There is limited evidence that increasing B12 levels benefits people without B12 deficiency [51] .

B12’s impact on cognitive health may involve multiple mechanisms, including brain volume and function [52] . However, more extensive research is needed to fully understand its effects and potential as a cognitive enhancer.

Thesis Motivation contains 1000mcg. The research states that it may have no effect if you’re not Vitamin B12 deficient.

Forskolin (Speculative)

Forskolin has only been studied in rodents regarding cognitive function. Forskolin is an herbal extract that shows the potential to improve memory and reduce Alzheimer’s disease symptoms.

Studies have shown that it restores nest-building and social behaviors in mice with Alzheimer’ s-like symptoms, reduces amyloid plaque deposition, and regulates brain inflammation [53] .

Forskolin also influences memory and tau protein phosphorylation in the brain, which is relevant in Alzheimer’s [54] .

Additionally, forskolin has shown protective effects against Huntington’s disease-like neurodegeneration in rats by improving learning and memory and reducing oxidative stress [55] .

These findings indicate forskolin’s potential as a neuroprotective agent for certain neurological conditions, at least in rodents.

I’m skeptical whether 250 mg of Forskolin in Thesis Motivation will help you “feel” more motivated.

Artichoke (Speculative)

Artichoke extract is known for its prebiotic properties and promotes probiotic bacteria growth in the gut, potentially benefiting cognitive functions in mice [56] .

In elderly individuals with mild cognitive impairment, combining artichoke extract and aerobic training improved cognitive status and reduced blood glucose and insulin resistance [57] .

Artichoke varieties Spinoso Sardo and Romanesco Siciliano demonstrated antioxidant properties and potential protective effects against cardiovascular and neurodegenerative disorders, with Romanesco Siciliano showing higher antioxidant power [58] .

The 450 mg dose is well under the dose used in these studies.

Thesis Confidence Blend Ingredients

Saffron (speculative).

Saffron is traditionally used in herbal medicine and shows promise in improving cognitive function in individuals with Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI) [59] .

Research indicates that saffron’s effectiveness is comparable to common drugs used for these conditions without increasing side effects. It’s also well-tolerated in cognitively normal individuals [60] .

However, most current studies have a high risk of bias. More comprehensive, low-bias clinical trials are needed to confirm saffron’s potential as a treatment for cognitive impairments like AD and MCI.

All of the research used 30 mg of saffron daily. Thesis Confidence has 28 mg, and I’m unsure why they formulated it without the extra 2 mg.

Magnesium Bisglycinate

Magnesium is essential for brain functions and has been researched for its potential cognitive benefits. Magnesium is particularly effective in increasing brain magnesium levels and has shown promise in improving memory and cognition in healthy adults [61] .

However, its role in anxiety and mood disorders is less clear [62] .

Studies indicate magnesium may help reduce symptoms of depression, but results are not consistent across all mental health conditions [63] .

Further research is needed to conclusively establish magnesium’s effectiveness and appropriate use as a therapeutic supplement in various psychiatric and cognitive disorders [64] .

500 mg of magnesium may help if you’re deficient, but there’s no clear benefit to making you more confident.

Sage (Speculative)

Sage, also known as Salvia, has traditionally been known to enhance memory. A recent study supports this, showing that acute ingestion of sage oil can significantly improve immediate word recall in healthy young adults [65] .

This suggests that sage may positively influence cognitive functions like memory, potentially due to its acetylcholinesterase inhibition activity in the brain.

However, this has not been replicated.

While historically used for various mental disorders, such as depression and age-related memory loss, contemporary research is needed to fully understand its benefits and potential as a cognitive enhancer.

Regardless of the 333 mg dose, this is one of the more speculative ingredients in all Thesis blends.

Sceletium Tortuosum (Speculative)

As mentioned in the Creativity Blend, Sceletium Tortuosum is known for its mood-enhancing properties. The same 25 mg dose is used in human trials.

Magnolia Bark (Speculative)

Magnolia officinalis is commonly used in traditional medicine for mental disorders like anxiety and depression and shows potential as a nootropic supplement.

Studies have demonstrated that its ethanol extract can improve cognitive function and memory in stress-induced situations. It also exhibits anxiolytic properties, reducing anxiety-related behaviors in rats [66] .

The extract’s effectiveness is also evident in lowering stress-induced increases in corticosterone and tyrosine hydroxylase levels.

Moreover, Magnolia officinalis, especially its component honokiol, has neuroprotective effects and can regulate mood disorders by modulating GABA and CB1 receptors in rats [67] .

These are rodent studies, so they cannot be extrapolated to humans. Regardless, they are included based on the mechanistic data and the theory that the 10 mg dose does the same thing in humans.

Ashwagandha Leaf & Root

The 120 mg of root and leaf ashwagandha may be enough to have a nootropic effect as the extract dose is between 100-1200 mg, as stated in the Creativity Blend section. However, this is root and leaf, and the main benefits are derived from the root.

Thesis Logic Blend Ingredients

Ginko biloba.

Ginkgo biloba is extracted from the leaves and fruit to improve cognitive function. Its compounds include antioxidants, enhance blood flow, and have anti-inflammatory properties.

Ginkgo biloba extract has been shown in animal studies to help with chronic brain difficulties by modifying inflammatory mediators and the cholinergic system [68] .

Clinical trials have shown it to improve working memory and processing speed [69] . However, its usefulness in healthy people under the age of 60 is debatable [70] .

Typical daily doses vary from 120 to 300 mg. Although side effects are uncommon, they can include stomach irritation and headaches, which may cause blood to thin, affecting people on certain drugs.

Thesis Logic contains 160 mg of Ginkgo Biloba, which is within the recommended dosage range.

Theobromine

Theobromine is a compound found in chocolate and has been studied for its potential cognitive effects.

Research indicates that theobromine might have a lesser immediate nootropic effect compared to caffeine but could have neuroprotective benefits with long-term consumption, possibly reducing Alzheimer’s disease-related pathology [71] .

Further studies are needed to fully understand its impact on cognition.

Additionally, theobromine’s effects on mood and vigilance appear to be different from caffeine, with some studies suggesting it might not significantly influence these aspects in nutritionally relevant doses [72] .

However, combining theobromine with caffeine could modify its effects, potentially offering cognitive and mood benefits without significant blood pressure increases [73] .

More research is required to confirm theobromine’s cognitive and mood-related effects.

Thesis Logic contains 100 mg of theobromine, but it seems doses greater than 400 mg are needed to enhance cognition.

Phosphatidylserine

Phosphatidylserine is essential for proper brain function. Phosphatidylserine has been proven to be critical for maintaining nerve cell membranes and myelin, which is required for successful neurotransmission [74] .

Phosphatidylserine can help reverse cognitive loss as the brain ages by boosting cognitive activities such as memory formation, learning, concentration, and problem-solving [75] .

It is well absorbed in humans and crosses the blood-brain barrier.

Supplements containing phosphatidylserine have been shown to increase cognitive functions and are generally well-tolerated. Dosages ranging from 100 to 800 mg per day are advised for cognitive support [76] [77] .

Thesis Logic contains 400 mg of phosphatidylserine, which may provide you with these cognitive-enhancing effects.

High DHA Algae

DHA is a vital component of neuronal membranes and plays an important role in brain health and cognitive function.

DHA consumption improves adult cognitive abilities, especially when paired with eicosapentaenoic acid (EPA) [78] .

This impact is most noticeable in older people who have mild memory problems. Higher DHA and EPA doses (above 1 g per day) have been associated with better episodic memory.

Observational studies also show a link between DHA/EPA intake and memory performance in the elderly. DHA, both alone and in combination with EPA, improves memory in the elderly.

Thesis Logic contains 200 mg of DHA, suggesting insufficient DHA to provide a benefit.

Triacetyluridine (Speculative)

Triacetyluridine is being explored as a potential treatment for bipolar depression. In a study involving eleven patients with bipolar depression, high doses of triacetyluridine (up to 18 g per day) were administered over 6 weeks [79] .

The study measured the effects on depression symptoms using the Montgomery-Asberg Depression Rating Scale (MADRS) and evaluated cellular bioenergetics using phosphorus magnetic resonance spectroscopic imaging (P-MRSI).

Results indicated significant early improvement in depression symptoms.

Additionally, triacetyluridine responders showed notable differences in pH changes from baseline, suggesting triacetyluridine may improve mitochondrial function and reduce symptoms of depression.

Thesis Logic has 30 mg of triacetyluridine, which is well below the dose used in this study.

Bacopa Monnieri

Bacopa monnieri is a traditional plant that has been shown to improve cognitive performance, particularly memory.

Studies have demonstrated that bacopa extract, specifically bacosides A and B, increases memory formation, recall, and cognitive function [80] .

It has neuroprotective properties and is used to treat cognitive dysfunctions such as Alzheimer’s disease.

Adults should take between 200 and 400 mg each day. Bacopa is generally well accepted, with only rare reports of mild drowsiness or stomach difficulties.

Clinical trials show that older people have better memory, attention, mood, and overall cognitive ability [81] [82] [83] . However, more research is needed to thoroughly grasp its usefulness across many cognitive domains.

Thesis Logic contains 320 mg of Bacopa, giving you the efficacious dose to feel these benefits.

Thesis Nootropics Price

Thesis has two options: one time purchase or a subscription. Here’s how the prices break down:

• Subscription = $79
• One Time Purchase = $119

This is regardless of whether you purchase a personalized starter kit or build your own box.

You can’t buy them individually, either. You must purchase four boxes. When building your own, you can choose whether you want four of the same blend or mix and match.

They want you to try each blend for a week as part of the starter kit (there’s only a week’s worth of each blend in each container) to see which you like best.

Thesis has positioned itself as the most expensive nootropic available by adding the personalized element.

Is Thesis Nootropics Really Personalized?

I went through the initial quiz to see how they “personalize” their nootropic stack.

Here is what they recommended me:

Look, I get the marketing angle. In no way is this a truly personalized nootropic product. It’d be nearly impossible to create custom formulations for every unique individual.

However, the fact they have multiple blends means people can experiment to find which works best for them.

I will say, though, that if you choose the caffeine options, every blend will work. Many of the ingredients used in these blends are speculative and only based on animal research, and many are underdosed.

Benefits Of Thesis Nootropics

Multiple blends for different purposes.

To be honest, this benefit is more of a marketing tactic. However, some people may find certain blends jive well with them over others, giving you options within the same brand.

Further, Thesis claims the ingredients in each formulation work synergistically. There’s no research to back that claim, but at least know there are no negative side effects from their interaction.

Options For Stimulants Or Not

You can choose whether or not to include stimulants in your Thesis Blends. If you add the caffeine and L-theanine nootropic stack, the most potent synergistic brain booster, every blend will provide similar benefits.

However, if you’re already a coffee addict or plan to take Thesis in the evening, having no stimulants is the better option.

My Experience With Thesis

Based on my quiz, I was recommended Thesis Clarity, Logic, Motivation, and Confidence Blends. I tried each for a week to see if one stood out. I took them without caffeine as they all work if you have the caffeine L-theanine stack.

I have to say the Confidence and Motivation Blends did absolutely nothing for me. I didn’t “feel” any brain-boosting effects or feel more confident or motivated.

The Logic and Clarity Blends had small positive effects on my concentration on mentally demanding tasks like writing, coaching, or podcasting.

If I were to continue taking Thesis, I’d opt for either of these two blends.

Who Is Thesis For?

Busy working professionals.

Thesis Nootropics are ideal for busy professionals facing demanding schedules and high-stress environments. These blends can help enhance focus, improve decision-making, and increase productivity.

They are designed to support sustained mental energy throughout the day, enabling professionals to manage their workload more effectively without the usual mental fatigue.

Creative Artists

For creative artists, Thesis offers blends that stimulate creativity and enhance divergent thinking. These nootropics can help break through creative blocks, foster innovative thinking, and maintain a heightened state of inspiration.

They are particularly beneficial for artists seeking longer periods of creative flow and those seeking fresh perspectives.

Students can significantly benefit from Thesis Nootropics, especially during intense studying or when facing challenging academic projects.

The blends are formulated to enhance memory retention, improve concentration, and boost learning capabilities. This makes them a valuable tool for students who need to absorb and retain large amounts of information and perform well in academic assessments.

Gamers find Thesis Nootropics beneficial for improving their gaming performance. The blends can enhance reaction times, increase focus, and improve strategic thinking skills.

They are particularly useful during long gaming sessions, helping gamers stay alert and responsive, which is crucial in competitive gaming scenarios.

Coffee Haters

Thesis Nootropics provides an excellent alternative for those who dislike coffee or want to avoid caffeine jitters.

These blends offer a way to boost mental energy and alertness without relying on caffeine. This makes them ideal for individuals sensitive to caffeine or those seeking to reduce caffeine intake while maintaining high cognitive function.

User Testimonials And Reviews

You can’t access the review database on the Thesis website, so I did some digging to find user reviews. Here’s a couple of positive reviews:

“I must admit that during the weeks that I consistently take them, I perform better & I generally feel better just knowing I’ve ingested something intended to positively alter my natural brain state. Minor tasks/chores no longer seem as daunting and I get this underlying kick to complete my work well.” – ParsnipExtreme2502 (Reddit)

“I didn’t find Weeks 1 and 4 to do anything for me, but Weeks 2 and 3 really helped avoid the post-lunch, post-work slumps I tend to get now that I’ve been working from home; Energy is especially useful for days when I haven’t gotten enough sleep the night before.” – leftylucy88 (Reddit)

I can’t find many negative reviews other than potential side effects like migraines, which can be caused by many different factors.

Thesis Side Effects

Side effects are rare from the ingredients in these blends. I personally didn’t have any adverse reactions to the four blends I tried. However, like any supplement, they may have potential side effects.

Consult with a healthcare provider before starting any nootropic regimen, especially if they have pre-existing health conditions, are pregnant or breastfeeding, or are taking other medications.

Thesis Alternatives

If Thesis Nootropics isn’t quite the right match for you or you’re just curious about other products, here are some alternatives I’ve tried and can provide an insider’s look into.

SAP Nutra nootropic Nooceptin improves memory, concentration, and cognitive performance without stimulants. It offers gradual brain health gains.

It improves memory and focus and provides a prolonged boost without a caffeine crash. Students, gamers, professionals, and seniors should use Nooceptin to boost cognition.

This brain supplement contains Lion’s Mane Extract, Citicoline, rhodiola rosea extract, L-theanine, Bacopa Monnieri, ginkgo biloba, and panax ginseng.

Some of these compounds have been shown to be useful, but others are experimental. Nooceptin, a non-stimulant method for long-term cognitive enhancement, usually works after 7-14 days.

Despite the risk of underdosed components and increased cost, Nooceptin may provide a stimulant-free cognitive boost.

Read more in our Nooceptin review .

Mind Lab Pro

Mind Lab Pro is a popular nootropic that has gained appeal as a result of its alleged cognitive benefits.

Pure substances are used in its formulation, which is intended to improve mental clarity and attention. It is stimulant-free, making it an excellent choice for anyone seeking a well-rounded routine.

Its unique combination of 11 research-backed components distinguishes it from competitors in the brain health supplement sector.

These compounds were carefully chosen to help cognitive processes like memory, focus, mental clarity, mood, and cognitive processing speed.

Despite some criticism about the quantity of specific substances and the need for more scientific data, Mind Lab Pro has earned worldwide recognition for its ability to improve cognitive performance in professionals, students, the elderly, and athletes.

Our Mind Lab Pro review goes into great detail.

Braini distinguishes itself by being stimulant-free, providing long-term results, and having a short ingredient list focusing on long-term cognitive gains. It does not, however, deliver the immediate euphoric boost that some users may expect from a brain supplement.

Peptylin, a silk protein peptide with neuroprotective effects and potential benefits for executive function; NeurXcel, which is rich in omega fatty acids; and Wild Canadian Blueberry extract, which is known for its antioxidant characteristics and cognitive support, are all key ingredients in Braini.

Braini is backed by clinical trials, a 60-day money-back guarantee, and a 30-day challenge to scientifically quantify changes in brain function.

Our Braini review contains an in-depth breakdown.

Vyvamind is a nootropic supplement containing caffeine and L-theanine. It helps users focus and improve cognitive performance. Users claim increased focus, vitality, and cognitive abilities without big crashes.

Vyvamind’s formulation, which contains less L-tyrosine and citicoline than some studies suggest, is intended to supplement the major nootropic duo of caffeine and L-theanine.

This combination is well-known for boosting concentration and cognitive function. The supplement is touted as a non-stimulant alternative, appealing to clients seeking a more natural and less intensive approach to cognitive growth.

Vyvamind is suitable for coffee-averse people, busy professionals who require a focus boost, and students during study sessions.

Our Vyvamind review goes into great detail.

Because of its purported fast cognitive effects, NooCube is a popular brain-boosting product. It contains ingredients such as Bacopa Monnieri, L-tyrosine, and L-theanine.

These are well-known for their mental health advantages. However, several compounds, such as Huterzine-a and Alpha GPC, remain speculative without additional investigation.

NooCube is intended to improve cognition and alertness without using stimulants, and the amounts of each ingredient are clearly labeled.

Because it gives different cognitive benefits without the jittery side effects associated with caffeine, NooCube is especially good for working professionals, students, elders, gamers, and combat athletes.

Our detailed analysis can be found in our NooCube review .

Frequently Asked Questions

What is thesis nootropic and what does it do.

Thesis Nootropic is a personalized supplement formulated to enhance cognitive functions. Depending on the blend chosen, users can expect improvements in focus, reduction in procrastination, stress management, and memory recall.

Does Thesis Work Like Adderall?

Thesis Nootropics and Adderall are used to enhance cognitive functions, but they are fundamentally different. Adderall is primarily prescribed for treating Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy.

Adderall is an amphetamine, classified as a controlled substance due to its strong stimulating effects and potential for abuse and dependency.

Thesis Nootropics are dietary supplements designed to enhance healthy individuals’ cognitive functions, such as memory, focus, and mental clarity. They are not intended to treat medical conditions like ADHD.

How Long Does It Take Thesis Nootropics To Work?

If you have the caffeine version, within 30 minutes. You may feel the non-stimulant blends kicking in just as quickly, but they won’t be as pronounced. Sometimes, they can take multiple weeks to feel them working.

I’ve explored the world of nootropics and shared my firsthand experience with Thesis Nootropic’s various blends. While personalization is nothing more than a marketing tactic, the different blends are a nice touch for those who want to experiment with different ingredients.

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What Is Thesis?

How does it work, thesis nootropics benefits, thesis blend breakdown, thesis energy benefits, clarity benefits, motivation benefits, logic benefits, creativity benefits, side effects, who should take it, who shouldn't take it, where can you buy it, other user reviews, how does thesis compare to other supplements, our verdict on thesis nootropics.

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• ThesIs Nootropics Review

Thesis Nootropics Review (2024) Is It Worth The Hype?

As a fitness coach, I've seen the impact of high-quality nootropic supplements on motivation and concentration during workouts.

Teaming up with my dietitian and 12 clients, we documented the significant cognitive benefits and general effects of Thesis over a period of four weeks.

Does it genuinely fulfill its promise of enhancing your mental performance and focus?

Before trying out the supplement, keep reading and find out if it's right for your mental wellness needs.

Thesis is a stack of supplements that aims to improve cognitive function, mental stamina, mood, and overall mental energy levels.

Thesis nootropics' energy formula claims to boost energy levels while catering to individuals following a certified gluten-free diet, promoting positive habits and supporting nerve health.

What's particularly interesting about purchasing this stack is the Thesis algorithm.

It’s a set of questions that assess your personal needs to create a bespoke starter kit.

More on this shortly.

As a result, you get a recommendation from a couple of their products to provide personalized blends for nootropics.

Let’s learn more about how Thesis supplements work with your brain health.

Thesis Nootropics

Rated With Total Shape's Scoring System

The Thesis experience begins with a questionnaire to assess your needs and goals, like improved physical and mental energy.

Based on your responses, the algorithm will recommend different Thesis blends to help you achieve your goals.

After going through the quiz, you get a recommended Thesis starter kit.

The five different products Thesis then recommends claim to work similarly to smart drugs by boosting your cognitive function and mood.

But unlike prescription medications, Thesis uses natural ingredients like vitamins, amino acids, minerals, and herbs.

“Nootropics, a greek word meaning 'Towards the Mind', are compounds that are both (1) neurologically active and (2) directly or indirectly enhance cognitive potential via increased capabilities (ie. reflexes), state of well-being, or learning potential.” - Kamal Patel, MPH, MBA at Examine.com

Once you are a Thesis customer, you can also set up a meeting with a Thesis coach to review your stack and the effects you are looking for and experiencing.

But does that make Thesis legit?

Let’s see what our detailed clinical research reveals.

The first thing that we got our testing team to do is to go through a full week of keeping an hourly journal to self-evaluate their mood, concentration, and cognitive function.

Then we put them through three weeks of taking their Thesis recommended stack and got them all to keep their hourly journaling going.

The first thing we noted was that the energy blend and creativity formula seemed to give our clients a good boost in brain performance.

And the folks that took the motivation blend a few hours before heading to the gym also found they were more focused on their workouts.

However, the majority of our test group highlighted that the effects seemed to wear off after about 4–5 hours.

We also noted that the logic formula didn’t provide a huge benefit, which could be down to a lack of a proven formula.

We also found that the Thesis nootropics cost can mount up if you want to stack a few of them.

• Allows you to combine different product formulas for personal goals
• Provides support from coaches to help you refine your stack
• Positive impacts on mood and concentration levels
• Some of the ingredients are not supported by reliable clinical trials
• You may need to swallow quite a few capsules, depending on your particular blend

Thesis Nootropics offers a unique blend of ingredients that target thesis energy, thesis creativity, cellular function, and even skin health, making it a notable contender in the supplement industry.

For this part of the Thesis supplements review, I got my dietitian to help out and analyze the Thesis formula for each of the products.

We also tested the effects with 12 clients to see whether the marketing hype lives up to expectations.

Let's have a more detailed look at the features and benefits of each blend.

The idea behind Thesis Energy is to help people clear brain fog and feel more mentally energized.

To verify this, we paid close attention to the journal entries our testing team made in the afternoons. This is typically when people feel a slump.

What we found was that folks who took this supplement after lunch gained some mental clarity.

But it seems like the effect wears off after about four hours, so you don’t gain an all-day effect like with other nootropics.

Key Ingredients:

• Choline: According to PubMed, this mineral may boost memory function and verbal fluency [ 1 ].
• L-Theanine: A controlled trial posted in Nutritional Neurosciences suggests that this amino acid can work well with caffeine to increase alertness without causing jitters [ 2 ].
• Caffeine: This stimulant can boost alertness, but you can get this from a morning coffee, so I’m not overly impressed that it’s added here [ 3 ].

Thesis Clarity is another product that aims to improve neural communication and allow you to think more clearly and effectively.

Thesis Nootropics' clarity formula provides an extra boost of cognitive performance, targeting stress response reduction and improving sleep quality, all while delivering a healthy dose for enhanced mental clarity and improved ability.

We did note in our testing review that there seems to be an improvement in mental function for several hours after taking it.

But this also seemed to happen more with those testers who took the clarity and energy formula.

• 7,8-DHF: Studies have shown that Dihydroxyflavone can cross the blood-brain barrier and act as a neuroprotective ingredient [ 4 ].
• Alpha GPC: This is an ingredient that has been shown to protect against neurological decline [ 5 ].
• Lion’s Mane: This mushroom is common in nootropics and has been shown to improve mental performance and creativity [ 6 ].

A large part of improving mental health comes down to how focused and motivated you are with daily tasks. Our clients who tested the Thesis Motivation noted that it seemed to help them remain more motivated during workouts.

But this doesn’t seem to happen if you take it in the morning and go to the gym later in the day. So you’d need to get your timing right.

• L-Phenylalanine: Research has shown that this ingredient can help with signs of depression and improve overall mood [ 7 ].
• Dynamine: Also known as Methylliberine, studies have highlighted that it can impact your mental well-being when combined with caffeine [ 8 ].
• Forskolin: The interesting thing about this herbal ingredient is that it can improve blood flow to the brain for better focus and motivation [ 9 ].

For this product, we looked at what our clients noted in their journals when they were at work or studying. While they did find a boost in focus, none of them noted that it helped improve verbal fluency or problem-solving skills.

• Ginkgo Biloba: This is a common ingredient in traditional medicine, but modern clinical trials have shown that it can help brain health through improved blood flow and anti-inflammatory properties [ 10 ].
• Ashwagandha: This herb can have a direct impact on stress and memory, allowing you to think clearly and effectively [ 11 ].
• Saffron: It’s the most expensive herb in the world, and studies have linked it to improved stress, mood, and cognitive capacity [ 12 ].

A few of our clients tried the creativity blends, but this is one of the products where most of them didn’t report any significant improvements.

Combinations with other products above did positively impact mood and stress, but we couldn’t find any comments where our clients highlighted that they felt more creative in their work or any other creatively demanding context.

• Agmatine: This amino acid doesn’t just boost cognitive performance but may also help to protect brain cells against oxidative stress [ 13 ].
• Zembrin: Research has shown that this herb can impact both stress and anxiety, but there’s no specific evidence that it can help with creativity [ 14 ].
• Ginseng: This is a common ingredient in diet supplements as it can improve blood sugar levels, but that wouldn’t directly influence creativity [ 15 ].

We also asked all of our clients to provide any feedback they had on side effects related to the nootropic blends.

Overall, the majority of people found that it didn't cause any major issues.

We only noted that one person had a bit of a rash, which could have been a result of an allergic reaction to one of the ingredients.

We also found that it’s best not to take these capsules on an empty stomach. Ideally, take them within 20 minutes of eating a meal to avoid stomach upset.

Based on my personal experience, people who want to achieve a moderate boost in brain function may want to take nootropic supplements.

You would need to experiment with the timing as these capsules don’t provide effects for the entire day. But after about a week, you should be in a position to spread out the capsules for maximum effect.

You can also contact a coach directly for advice on timing. It's especially important when you have no prior experience in taking these supplements. However, a good starting point is to take the minimum and adjust from there.

Based on our own experience, people with high blood pressure or neurological diseases shouldn’t take Thesis natural nootropics to enhance cognitive function.

In such cases, it’s best to have a doctor review your detailed medical history and the nootropic ingredients for any potential side effects.

Our testing team didn’t note any improvements whatsoever, and when we specifically asked them after the trial, none of them said they saw a noticeable difference.

You can buy Thesis Nootropics directly from the company website.

We generally recommend avoiding third-party retailers to ensure that you always get the real product, so this is a positive highlight.

We placed two orders, and the package arrived within four days, which is about average for nootropic supplement companies.

One thing to point out on the Thesis supplements shipping policy is that currently, the company doesn’t offer international shipping.

We also had a look for other nootropic reviews online to see what users were saying.

“It gave me more energy. I have struggled with low energy and I felt like my old self again. I could get up & get things done.” - Laurie C., taketheseis.com

“After 1 month of using Energy, Creativity, Clarity and Logic pack, I do not note any difference in mindset. I opted for the non-caffeinated blends as I am not a big caffeine person to begin with so a caffeinated blend might show some improvement.” - Beefnug, Reddit

“I have been continuously nauseated every day using thesis packets. I have given it a week and a half and cannot handle the negative side effects. Disappointed.” - AdGroundbreaking5162, Reddit

Our Thesis scientific research suggests that it doesn’t compare well to our testing of three other products for improving cognitive function.

First of all, we looked at the results we have for Mind Lab Pro .

The one thing that stands out the most is that it seems to be effective for many more hours than Thesis, so the timing doesn’t become an issue.

The second one we compared is Onnit Alpha Brain . This nootropic supplement seems to provide a lot more focus and motivation, especially while you’re at the gym.

Compared to Gorilla Mind Smooth , Thesis doesn’t have the same effect on boosting energy and reducing stress.

Related Articles:

• Avantera Elevate Review
• Best Nootropics For Men
• Best Nootropics For Women

Is It Safe To Take Thesis Nootropics Every Day?

Yes, it is safe to take Thesis Nootropics every day. We found Thesis to be generally easy to process, but you need to look out for allergies to any of the ingredients. A good way to do this is to ask your physician for advice since they will know whether these ingredients are good for your health.

Does Thesis Nootropics Contain Banned Ingredients?

No, Thesis Nootropics doesn’t contain any banned ingredients. All of the ingredients are based on minerals, amino acids, and herbs that won’t cause a positive drug test result.

Based on our feedback from a nutritionist and the test results with 12 clients, we don't recommend Thesis.

Not only do its effects wear off after a few hours, which makes timing your intake a problem, but it also burns a hole in your pocket for just a stack of three or four products.

Instead, I highly recommend one of the best nootropic brands we have tested so far: Mind Lab Pro .

Our results show that its effects last for most of the day and provide great clarity, energy, focus, and concentration, making it a favorite among clients of all age groups.

We Recommend This Instead

Mind Lab Pro

• Great combination of herbs and amino acids that work as a cognitive enhancer
• Added B vitamins to support red blood cell production and boosted energy levels
• Great feedback from users that it can help with relieving anxiety
• Get the BEST PRICE until the end of September
• The capsules are not the smallest ones to swallow

About The Author

James Cunningham is an author and dietary supplement connoisseur with a solid academic foundation, holding a BSc in Sport & Exercise Science from the University of Hertfordshire. Specializing in Performance Psychology, his expertise is backed by both rigorous study and practical experience.

As an author, James is committed to guiding his readers towards optimal health and performance, providing actionable insights and strategies through his writings.

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Thesis Review | I Tested this Nootropic for 4 Weeks, Did It Work?

In this Thesis review, we’ll take a long look to this nootropic company that offers combinations of various nootropic blends that are tailored to best suit your individual needs.

Those brain supplements comprise of the following blends.

If you have been struggling with anxiety, stress, productivity or energy, you might have certainly looked at brain supplements. These are usually generic blends of natural herbs and mushrooms with positive effects in various areas and processes in your brain.

Table of Contents

Thesis Review at a Glance

Approach to This Thesis Nootropics Review

As I alluded to, Thesis presents a questionnaire so to individualize your box. It takes around five minutes to complete, and asks questions that are quantifiable, yes/no or degree based. Everything from your weight, age and sleep quality to how often you exercise, which unhealthy habits you indulge in and how much you procrastinate will all be on the table.

I’ll be taking four of the six blends for six day intervals and documenting my results. So by the time you’re reading this, I’ll have tried Thesis for the better part of the last month.

Thesis Nootropic Ingredients

The combined effects of caffeine and l-theanine in a 1:2 ratio have been proven to be optimal for cognitive performance and mood; which means that Thesis has a good base.

30-Day Thesis Nootropic Test and Results

As pictured above, I have the starter kit.

The kit includes four blends of your choice, each with six individually wrapped doses that are designed to be taken once daily. My kit contains the blends for Clarity, Creativity, Confidence and Motivation . As per the instructions, I’ll pick a blend, take it once daily for six days, with one day off. I’ll evaluate the results, then start the next blend.

A quick bit about me: large male, mostly sedentary with some high activity days, no chemical vices, mostly liquid diet as of late.

I’ll be taking each dose with food as recommended, likely with one our recommended meal replacement shakes such as Soylent, Huel , Ka’Chava or Rootana .

Week 1 – Thesis Clarity Review

Early on, the effects were pretty noticeable . I did feel more energized when performing physical activity. Also, I did feel more “locked in” when I had to focus, in particular with games that require high execution and fast reactions.

On the flipside, days when I didn’t have much going, I didn’t notice much of a difference. I didn’t feel need to do more, and without something to intently focus on, they may as well be water pills.

Week 2 – Thesis Motivation Review

Only three pills in this blend, so a bit easier to take.

Motivation is designed for task completion and focuses on reducing procrastination and stress. I did manage to stay focused on my current diet, though I feel that would have happened with or without these pills.

Week 3 – Thesis Creativity Review

Back to four pills with this one. The highlights of this blend focus on learning, memory and cognition.

At times I felt scattered, like I had to be doing something, which can be detrimental if you need to focus on a set of tasks. But I can see if I needed to innovate something, how this can help, being able to cycle through thoughts and ideas quickly.

Seemingly no ill side effects too. Pleasantly surprised considering I’m not at all very creative.

Week 4 – Thesis Confidence Review

Three pills, with two of them dark. Reminds me of hamster pellets. Moving on….

Of all the blends, I felt the effects of this one the fastest, usually within about 30 minutes, as opposed to an hour or so like the others.

It worth noting that this could also be to the accrual effect of having taking nootropics for the past 30 days. Most of the best nootropics take a while to showcase all their positive effects, as there’s a build up period.

Who Wrote the Thesis

“As long as I can remember, people thought I was stupid, lazy, or unmotivated. I started to believe it. In school, I would read the same page over and over again, without absorbing anything. At 16, I dropped out of high school and went to work at a sandwich shop. Fast-forward ten years — I scored in the 99th percentile on the GMAT and earned Master’s degrees from Yale and INSEAD. Nootropics turned everything around for me and helped me form the positive habits that I built my success on. Once I balanced my brain chemistry, I could perform like never before. Dan Freed

Price and Shipping

Thesis supplement can be purchased as a single box, or part of an ongoing subscription. You choose which blends you prefer and they are shipped to you monthly.

Shipping is only within the US, and is free via USPS First Class Mail.

Are Thesis Personalized Nootropics Worth It?

Regarding the price, Thesis offers a very competitive offering when compared to the best Nootropics like Hunter Focus .

Thesis makes this easier, which is already a big plus, and you could see bigger benefits than with other competitors.

Taken that into consideration, I believe that Thesis nootropics are worth it for those considering regular use to improve cognitive function and long-term mental health.

Customer Thesis Nootropics Reviews

That said, reviews on their site are overwhelmingly positive. Not all products seem as effective, as discussed in our tests, and Creativity and Clarity seem to be the least liked. On the other hand users liked Motivation and Confidence the most, unlike me.

I’m going to be honest with you, I was skeptical but I started a new job so I thought maybe it could help.Within a half hour of the first time taking it I saw immediate results.I’m more alert and focused than I’ve been in years.I’m so happy I found Thesis as it has been life changing for me so far. Elliot S, 5-star

I have been off stimulants for months now and these formulas are far superior. My husband and daughter both noticed the change and said I have been more productive, focused, less anxious, and more “thinking outside the box”. I have tried for years to get off stims and nothing would work. Thank you for making such an amazing product. Debbie M, 5-star

If you’re new to nootropics, we can guide you to the blends we believe will work best for you based on your lifestyle and goals. You can make adjustments to these blends based on what works best for you.

Our Starter Kit is designed so that you can try multiple formulations to identify which nootropics work best with your unique brain chemistry. Each week you will sample one of your recommended blends, and record how you respond. Things to note would include increased productivity, decreased procrastination, enhanced focus and any changes in your routine At the end of the first month, you should have a good idea as to which blends work most effectively for you. These will be the blends you will continue with in your next month.

We offer the most advanced nootropic system available, to find the exact compliment for your specific brain chemistry and desired areas of focus. Our innovative Starter Kit allows you to experience multiple formulations, and determine what works best. Our process is complex because we’ve found that it yields the best results in the shortest amount of time. If we could formulate one pill that would work for everyone, we would! Because the human brain is deeply complex, that is just not possible.

Depending on your genetics and experience with nootropics, the effects can be felt in as little as 30 minutes after taking each blend. Nootropics have the most impact when taken on an empty stomach, just after waking from a normal night of rest. Some people may need a few days of consecutive use to feel the effects of the nutrients.

Verdict: Thesis Nootropic Review – 4 Weeks with Noticeable Effects

I find the approach that Thesis is taking to be a sound one. While some may be annoyed or turned off by the initial quiz, it’s certainly a necessary step in the overall process of finding which blends work for you, and which you should avoid. Also, without it, it would be a one size fits all product, and there are plenty of those already on the market.

Personally, I thought that Clarity and Creativity did the most for me . They each had noticeable effects that were largely in line with what was expected. Motivation and Confidence I wouldn’t have again, as Motivation seemed to to correspond with poor sleep and Confidence just didn’t provide enough of a benefit for me.

Bottom Line – If serious about adding nootropics to your routine, Thesis offers a great way to find what’s best for you.

Thesis Nootropics

Ingredients, effectiveness, nootropic blend.

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3.7 • 71 Reviews

Thesis offers a range of personalized nootropic supplement formulas to enhance your mental performance.

Thesis reviews

65 % of reviewers would recommend to a friend

Reviews mention

• Enhanced focus and motivation
• Effective alternative to medication
• Noticeable energy boost
• Supportive customer service
• Possible jitteriness from caffeine
• Ineffectiveness for some users
• High price point
• Challenging subscription management

Thesis, a brand offering blends of nootropics and adaptogens, garners mixed reviews. Users praised the brand for significantly enhancing their focus, motivation, and energy levels, with some comparing the effects to ADHD medication. However, others found the blends ineffective or too strong, leading to side effects like jitteriness. Some users also reported issues with high prices, frequent emails, and difficulty in managing subscriptions.

AI summary based on Thingtesting reviews

5 months ago

Thesis seemed like it would help with concentration, energy, and focus. However, the formula made specifically for my needs did not work, so I made up my own formula of supplements, and that did not work either. I would give it a try even though it did not work for me because everybody's mind is different, and it may work for you. It is, however, a pricey subscription as well.

3 months ago

It is nearly impossible to change or stop this subscription. Most products that I love, will notify you when they are about to ship and they make it easy to sign in and change items. I was lead to believe someone from Thesis would email me and ask questions about what I wanted to continue with, instead I received another two months of the starter kit. This bad business tactic leads me to believe the product doesn't work. I tried it the first month and didn't feel any different.

A little about my backstory: former pothead turned scientist looking for an edge in progressing through the corporate ladder. I had startedtaking lions mane, ginko biloba, gotu kola, d3, fish oil, etc, all with the goal of trying to replace anti-depressants, which "worked" but made me feel like a zomboid. That was in late 2022. When I tried "Clarity" I noticed that lions mane was an ingredient, but there were other things I had never heard of. I took my multi-v, omega/d3 and a pro-biotic in tandem with clarity, and within 3 days i could feel almost an "awakening" happen. I became motivated in ways i never had before... long had my mother always said I would be a good lawyer, so I went to grab an LSAT prep book just to see if I could even focus on it. I read through 100 pages in 3 days, and got 13/14 arguments correct in that time. But the way Thesis works (when you're starting out) is that you only have 6 days with each blend. My mother had gotten this trial pack for me as a gift. I made an account under my name and email and was unable to get 4 6-day packs of clarity out of the gate; you have to get a starter back with multiple blends first. Then only then it seems can you mix and match Thesis' 6 blends to your choosing. Thats a bit of a drawback honestly, but it is worth it to do the starter pack as they recommend... In my starter pack I also had Energy, Logic and Creativity. Energy was my least favorite as i kept my caffeine consumption normal, which can it seems cause jitteryness and irritability and an overal feeling of adrendal fatigue after the 3rd day out of 6. By day 6 i felt like a crackhead. Logic was the 2nd blend that I had tried. It had a very anti-depressant effect; nothing in my day to day felt difficult and I felt very at peace with my place in the world. Organization became slightly easier, and hard tasks at work became almost boring. Not quite as good at helping me focus on learning, but good at helping me access and remember what I already know. Creativity was a nice blend that probably had the least noticeable affect, but it was subtle and pleasant. I actually felt happy! I noticed my musicality became much more interesting (guitar player). Overall, their online menu is confusing and frustrating. You have the option of "order now" and then under that is the date your subscription will bill and ship your next set of blends. But it seems at first that if you're asking for an "order now" that it glitches out and says "wont get until 2 weeks after when you want it". This resulted in me spending literally almost 1,000 dollars in a singlr day (accidentally ordered 3 6-month subscriptions). But Alisha and Jo with customer service were able to get this resolved! Overall, the merit of the blend that I love, "Clarity", is worth all of the logistical trouble I had. I feel like a new person. And I was able to achieve the feeling naturally without abnormal psychiatric medication, which has a litanous history of side effects. Overall, I can't recommend this enough, especially for people like me who always felt mentally tired and depressed and unable to advance

It's called thesis because they want to see how many people feel better taking placebo. Other than giving you stomachache sometimes and taking your money, the pills don't do anything. I spent over 100, took the test, and religiously took all the blends. I'm telling you, I pero discovered that it's a scam.

Thesis will not let customers write reviews on their website. As far as I know the reviews on there are fake or hand chosen. They seamed to work well for daytime activities, we felt the focus and our brains activating. At night if we even had one drink after 5 peaceful years together violence erupted in our household repeatedly until we stopped taking them. Not just violence but brutal rage causing our divorce. We became embattled for seemingly no reason and could not deescalate the situation as we had done the 5 previous years. I will regret trying these for a long time to come. It’s one thing to give people drive it’s another thing to set them off into overdrive. These should definitely have a warning label, we could have stopped before it went too far. At the time we had no idea what was going on until it was too late and our lives are changed forever.

6 months ago

This product has exceeded all my expectations, outperforming any medication my doctor has previously recommended. It has profoundly improved my life, especially in managing my ADHD. Since I started using it, I've noticed a remarkable enhancement in my ability to think clearly, focus, and complete tasks efficiently. For someone with a lifelong struggle with ADHD, this product has been a breakthrough, allowing me to function better and with less stress. After using it for several months, I can confidently say that it has sharpened my cognitive abilities, often making me feel more intellectually advanced than many of my peers. Here's the secret that no one is telling you... Red Bull + Thesis + Healthy Food + Fitness = Happy Extraordinary Life!!!

I've been a fan of nootropics and adaptogens for a while now, and I must say these are probably my favorite option. Each blend has proven ingredients, alongside caffeine (optionally), and for me they truly do what they claim. They all bring me alertness and I am wide awake with a focused and balanced energy. I found myself more motivated, more productive, and in flow state with each blend. I took these in the morning on an empty stomach, or in the afternoon when I needed a boost & they never failed. I would recommend these to anyone looking for a natural boost. While Creativity was helpful in graphic design work, it's also recommended for social situations so I tried it once before going out with some friends and I undeniably felt more comfortable, relaxed, sociable and talkative. The logic & clarity blends worked wonders at work, and the energy blend was an incredible afternoon slump boost that kept me focused and alert until bedtime. I am super eager to try the motivation blend as procrastination is one of my weaknesses... but overall these have changed how I think of supplements or the typical things I would use for energy or focus. Game changers in my opinion!

10 months ago

These are pricey and I unfortunately cannot tell a difference when I take them. I was so bummed because I would love to hack my focus / creativity / clarity, what have you! What a dream! But I found, finally, 36 years into life, that my best bet is eating well sleeping well drinking less yada yada. I'm not a doctor but y'all should try that.

I've tried a fair share of nootropics and adaptogens and was excited when I heard about the thesis thingdrop since the price can be pretty steep. After taking it over this past few weeks, I am thrilled with it! I really do think you can feel the different effects depending on which one you're taking and I never felt any aches or pains regardless of taking it on an empty stomach or not. As stated, it's pretty expensive for a monthly subscription but that doesn't mean I won't splurge for it every once in a while. Looking forward to trying out the other formulas!

I finally managed to complete the four options included in the starter pack, and overall, I didn't see significant results. As a fan of nootropic supplements, I had rather high expectations for Thesis, especially considering their price point. Having different "formulas" for specific results might have led to a bit of a misconception. The reality is that when it comes to nootropics, my primary goal is to achieve a heightened state of focus, accompanied by an uplifting state of mind that supports my motivation, energy, and confidence. It feels somewhat odd to have four different products when what I truly seek from nootropics is clarity. In the end, I didn't notice substantial effects from Thesis compared to other brands I've tried. The branding looks fantastic, but it seems like you're purchasing a brand rather than a highly effective product.

Only done the Energy one so far and I think it might be working, not feeling a crash after my workouts. Will try the others and update as I go along.

Unfortunately I didnt have a positive experience with these, but I don't fault the product. One of the challenges with nootropics is that everyone's individual chemistry will react differently and I found that of the 4 different formulas, two made me feel overly aggressive and 2 did basically nothing. The effective ones were a bit insidious in that it took me far longer to notice the mood change than my husband, who knew I was trying these for a limited time and saved his feedback for after each formula's course. I did allow more than the recommended time between each formula so that I could assess the effects of each in isolation. I wouldn't recommend these to anyone who isn't at least moderately familiar with nootropics, or who isn't fairly in-tune with their mood.

I wanted to love this brand. Unfortunately out of the four blends I tried, none of them worked for me. I felt extremely off and weird when taking a couple of them. Nootropics affect everyone differently and I still recommend them to people looking for natural alternatives. Customer service is great, and shipping was fast.

I tried the variety pack and experienced significant results, with an increase in focus and motivation. The bundle is quite pricey for repeated purchases (so -1 point), so I identified the most effective supplements and were able to purchase them at a cheaper price for daily use. I also think the packaging could be consolidated to avoid so much waste. But these do really work!

This is probably the second or third nootropic supplement I've tried, and I just don't find them to make a noticeable difference in my daily life. Unfortunately, Thesis continues this trend. I followed the instructions and tried each formula individually for several days, waited a day (or more) and started the next one. Clarity gave me a gnarly stomachache, Logic and Energy probably were probably the nearest to actually making me feel positive performance, and I'm still taking the Creativity. I guess my brain chemistry (and Wellbutrin, lol) is too strong for these? Also, as much as I love the cute little packets, they made it difficult for me to remember to take the packets regularly since they were separate from my day-a-week pill case. I put them on my desk hoping it would help me remember to take them, and it did, though not as regularly as I probably should. As with anything that mixes with individual people's bodies, your mileage may vary!

I have mixed feelings on the supplements, but overall positive. I received the starter pack offered through Thingdrop, and have been trying each supplement both on an empty stomach and with food. I do think each supplement does what it says it does, but I feel some of the ingredients are kind of gimmick-y. For example, some contain Ashwagandha, and for Ashwagandha to actually have an effect for most people you have to take it daily for awhile. So these supplements are not going to have a transformative effect from just one dose. Another thing I noticed was almost all have L-theanine and caffeine in them, and I think these ingredients contribute to most of the effects of the supplements. I mostly noticed I felt more energized and focused with each of them, without much difference in my experience EXCEPT for the Energy supplement. That supplement turned out to be too strong for me on an empty stomach, and I definitely felt very awake and although not jittery, still felt over-caffeinated. I would try these again if I could afford to get the supplements regurarly, but the financial commitment is out of my budget right now. These would be good for a friend who can afford the high price to take the supplements as intended, and who is interested in health + wellness.

I will caveat this review by saying I don’t think I can really review supplements for their effectiveness, so will just speak to my experience. The packaging on these is nice, if a little wasteful, but I liked that each packet had the right mix of supplements (no playing mancala with my pill organizer). I also liked the idea of having different blends for different types of productivity. The idea is that you give each of the blends a good try (for a week each I think?) and then see which of the blends feels the best for you and your needs. I was going through a stressful time at a new job and was caffeinated within an inch of my life while trying these, so I’m not sure that any supplement could have broken through. It’s perhaps my own fault that I didn’t really feel the effects, but I do like the idea and would recommend to someone who’s looking for slightly more gentle forms of stimulants than pounding espressos until your ears are ringing.

Maybe these work great. Maybe they don't. What they do have is a bunch of caffeine - 100mg per dose. That's about as much as a cup of coffee. Since I've quit caffeine (it's been 9 months!) I don't want to try anything that could get me re-addicted. I'd love to test a caffeine-free version.

So, I got the Thingdrop trial pack with Confidence, Energy, Clarity and Creativity. While I love this product in theory, be wary if you are sensitive to caffeine because these four all have 100mg of it which is a little to high for me personally. It's akin to, if not a little higher than, a cup of coffee. = I do much better with 50-70mg, otherwise I get really anxious/jittery.

I didn't feel any noticeable difference or benefits, but with supplements I think they need to be taken over time to see improvements. That being said, without the thingdrop discounted price I don't think I would purchase again.

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Meet the wholistic research team.

Jacob Kovacs

Jacob Kovacs is a cognitive neuroscientist and the main author at WholisticResearch, specializing in nootropics and neuroactive peptides. His expertise in neuroscience and psychopharmacology bridges cognitive science with drug development. Kovacs’ work focuses on enhancing cognitive functions and brain health through innovative, efficient neuroactive compounds that overcome traditional pharmacokinetic challenges. His contributions are pivotal in advancing the understanding and treatment of neurological diseases.

Jason Williams, PhD

Jason Williams is a distinguished neuroscientist with a PhD in neuroscience from Princeton University and reviewer at WholisticResearch. His profound knowledge in neuroscience and pharmacology underpins his focus on nootropics and cognitive enhancement. Williams’ expertise is crucial in evaluating the latest developments in brain health and nootropic peptides for WholisticResearch. Beyond his professional pursuits, he enjoys balancing his rigorous research with leisurely walks with his dog.

George Collins

Contributor

George Collins is a neuropharmacologist specializing in neuroscience and a contributor at WholisticResearch. He holds a degree in neuropharmacology and brings a wealth of knowledge, particularly in nootropics, to his work. Collins has made significant contributions to research on prescription drugs, adaptogens, and cognitive enhancers. His insights, grounded in his experience from a leading peptide research lab, enrich the content on WholisticResearch, offering readers cutting-edge information on enhancing brain health and cognitive function.

Yoko Hill, serving as the editor at WholisticResearch, is deeply immersed in the world of neuroscience and cognitive enhancement. Her passion for neuropharmacology drives her exploration of various vitamins, nootropics, and dietary supplements. Hill’s commitment to optimizing cognitive function extends to her personal life, where she actively incorporates brain training apps and lifestyle adjustments. Her expertise and hands-on experience in these areas are instrumental in shaping the content and direction of WholisticResearch, ensuring it remains at the forefront of cognitive enhancement techniques and research.

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Total raised, last raised, about thesis.

Thesis is a company specializing in personalized nootropics designed to enhance cognitive performance. Their main offerings include supplements that support mental focus, energy levels, memory, and stress management, tailored to individual needs based on unique brain chemistry. The company primarily sells to individuals seeking cognitive enhancement and wellness support. It was founded in 2017 and is based in New York, New York.

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646-647-3599

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Jun 30, 2024

Sponsored Share This article provides detailed reviews of each option, highlighting their benefits, key ingredients, and user experiences to help you make an informed choice (Image: FIT LIVING) Nootropics are reputed to offer a range of potential benefits, including improved memory, enhanced focus, increased mental clarity, and better overall cognitive function. These supplements can be particularly beneficial for students, highly active professionals, or anyone looking to boost their brainpower and mental performance. If you're looking to try the best nootropics that actually work, like Thesis , you're in the right place. This article provides detailed reviews of each option, highlighting their benefits, key ingredients, and user experiences to help you make an informed choice. Best Nootropics of 2024 Mind Vitality - Top choice for cognitive performance and well-being BrainPill - Best for mental clarity Nootropics have the potential to help you boost your overall cognitive performance, and we have reviewed some of the best nootropics 2024 has to offer. From brands that let you customize your own blend to those that offer on-the-go options like gummies, we’ve covered a wide range of options so you can make the right choice. 1. Thesis - Best Nootropics Overall Key Features Pros Easy access to a wellness coach Promotes problem-solving skills Build your pack of blends or get a recommendation through a quiz Cons Who Is Thesis Best For? Thesis touts itself as an effective brain power booster for busy bees like you. This might be your jam if you wrestle with mentally intensive endeavors such as dealing with reports, getting lost in data analysis, or constantly brainstorming solutions. It comes in 6 different blends named after their benefits : Clarity, Energy, Motivation, Logic, Creativity, and Confidence. With any combination of these benefits, you can power through those demanding tasks without your brain going on vacation. Of course, check with a doc before diving in, but if you're looking for an edge, TakeThesis could be worth checking out. Key Ingredients Clarity 500 mg Alpha-GPC: Enhances cognitive function and memory by increasing levels of acetylcholine, a key neurotransmitter involved in learning and memory [1]. Energy 100 mg Caffeine: Boosts alertness and concentration, providing a quick increase in energy to improve mental focus [2]. Motivation 500 mg L-Phenylalanine: A precursor to dopamine, which is crucial for maintaining focus, motivation, and reward-seeking behaviors [3]. Logic 320 mg Synapsa (Bacopa Monnieri): Improves cognitive processing, learning rate, and memory consolidation, enhancing logical thinking and information processing [4]. Creativity 120 mg Ashwagandha Extract: Reduces stress and anxiety, potentially enhancing creative thinking by improving overall brain function and mood stability [5]. Confidence 28 mg Saffron: May improve mood and treat depressive symptoms, indirectly boosting confidence and social interaction abilities [6]. Pricing User Reviews There aren't many Thesis reviews out there, but we did find a couple on Trustpilot. Here's the skinny: it has a 3.6-star rating based on only 2 reviews. One person loved it and said it helped them ditch Adderall and feel more like themself. However, the other reviewer could have been more impressed, saying the pills didn't do anything, and they couldn't even unsubscribe. Try searching for independent Thesis reviews online or see if the company has a social media presence where you can check out what people are saying. Cons Who Is NooCube Best For? NooCube is like a brain gym membership for anyone who wants to level up their mental game. This supplement is one of the best nootropics for studying . It may help you be laser-focused, remember things like a champ, and ace those exams. Professionals, this one's for you too! If you work in a pressure cooker environment or juggle complex projects, NooCube may help give your brain the boost it needs to stay sharp, creative, and on top of your game. Key Ingredients The primary ingredients required for this blend are as follows: 20 mg Marigold Flower Extract (Lutemax 2020): Contains lutein and zeaxanthin, which support visual health and cognitive functions, potentially enhancing reaction times and spatial memory [7]. 100 mg L-Theanine: Promotes relaxation without drowsiness, improving focus and attention while reducing stress, making it easier to stay on task [8]. 250 mg Bacopa Monnieri: Enhances cognitive abilities by improving memory formation and reducing anxiety, supporting better learning and mental performance [4]. 20 mg Panax Ginseng: Boosts mental energy and reduces fatigue, enhancing cognitive function and overall mental performance under stress [9]. Pricing No binders or synthetic ingredients Its efficacy is backed by research Cons Who Is Hunter Focus Best For? Hunter Focus is like a brainpower buffet—anyone can grab a plate. Students, working warriors, creative minds, and even gamers—this supplement is designed to help you focus like a laser , sharpen your mental clarity, and basically become a productivity machine. In addition to being one of the best nootropics for focus, Hunter Focus may also support overall brain health . This way, you can keep your mind firing on all cylinders, no matter what you're tackling. Key Ingredients Concentration Activation 250 mg Citicoline: Enhances neural communication and increases the synthesis of acetylcholine, improving focus and mental clarity [10]. 500 mg L-Tyrosine: Supports the production of neurotransmitters like dopamine and norepinephrine, crucial for enhancing alertness and focus under stress [11]. Memory Matrix 500 mg Organic Lion’s Mane Mushroom: Supports brain health by stimulating the growth of nerve cells, which improves memory and cognitive function [12]. 300 mg Bacopa Monnieri: Enhances memory and learning by improving synaptic communication in the brain and reducing anxiety [4]. Mood Amplification 100 mg Phosphatidylserine: Vital for maintaining cellular function in the brain, helps mitigate stress, and enhances mood and cognitive function [13]. 300 mg Ashwagandha Root: Reduces stress and anxiety, promoting calmness and improving mental focus and stamina [5]. Pricing 2 Months (Brain Booster Pack): $180 4 Months (Ultimate Brain Power Bundle): $270 User Reviews Hunter Focus itself is under the radar when it comes to reviews. We could only find 1 on Amazon, and that person wasn't a fan of the caffeine content or price. However, the company behind Hunter Focus, Roar Ambition, has a solid reputation on Trustpilot with an average rating of 4 out of 5 stars from over 50 reviews. People love their customer service, the quality of the ingredients, and the fact that they use premium stuff in their products. May help manage some ADHD symptoms Cons Who Is Addall XR Travel Pack Best For? Addall XR Travel Pack is among the best over-the-counter nootropics for ADHD. It contains natural ingredients that may help reduce the symptoms of ADHD by increasing alertness and focus and reducing anxiety. However, the effects are generally mild compared to prescription ADHD medications. Addall XR Travel Pack is also perfect for jet-setters, busy bees at work, students on the run, or anyone who needs enhancing focus and mental clarity. Plus, this travel-sized pack is caffeine-free, so you don’t have to worry about the jitters and can power through your day. Key Ingredients Addall XR includes a 750mg proprietary blend of: Gamma-aminobutyric acid: Acts as a neurotransmitter inhibitor, promoting relaxation and reducing anxiety, which can enhance mental clarity and focus [14]. 1-Amino-2-Phenylethane: Thought to influence mood and cognition by affecting dopamine levels, potentially enhancing alertness and attention [15]. 2-Amino-6-Methylheptane: A stimulant that boosts energy and concentration, similar to caffeine but potentially with a longer-lasting effect [16]. Gelatin: While primarily used as a capsule component in supplements, it also provides glycine, an amino acid that can support cognitive function and sleep quality [17]. Pricing Cons Who Is Mind Lab Pro Best For? Mind Lab Pro is all about fast-acting brainpower. We're talking 30 minutes and you might feel like a whole new you . Imagine sharper focus, laser-like concentration for hours, and recalling things like a champ. Plus, you might feel more alert, clear-headed, and even a little happier. This nootropic is designed to boost your mental agility and motivation, making it one of the best nootropics for creativity. Key Ingredients 250 mg Citicoline: Enhances neurotransmitter levels, particularly acetylcholine, boosting brain function and improving focus and memory retention [10]. 500 mg Lion's Mane Mushroom: Promotes nerve growth factor synthesis, which aids in brain cell regeneration and improves cognitive functions like concentration and memory [12]. 75 mg Maritime Pine Bark Extract: Contains powerful antioxidants that support increased blood flow to the brain, enhancing cognitive performance and reducing oxidative stress [18]. 100 mg Phosphatidylserine: Vital for maintaining cellular function in the brain, it helps enhance memory, learning, and concentration and can also mitigate cognitive decline [13]. 50 mg Rhodiola Rosea: Acts as an adaptogen, improving the body's stress response and enhancing mental stamina, focus, and mood under stress [19]. 150 mg Bacopa Monnieri: Boosts brain function by enhancing synaptic communication, improving memory formation, and potentially slowing cognitive decline [4]. Pricing Who Is FOCL Day Stack Best For? FOCL Day Stack is your brain's best friend for busy days. Are you a student juggling classes and projects? A professional swamped with deadlines? This all-natural supplement is designed to help anyone conquer their daytime with laser focus, boosted energy, and sharper thinking . On top of being among the best nootropics for energy and focus, FOCL Day Stack is also caffeine-free, so you won’t experience jitters or crashes as you do with other nootropics. Key Ingredients 50 mg Organic Rhodiola Rosea: Improves mental performance and resilience against stress, improving concentration, mood, and overall mental stamina [19]. 5 mg Vitamin B6: Crucial for neurotransmitter synthesis, such as serotonin and dopamine, which are essential for mood regulation and cognitive function [20]. 150 mg L-Theanine: Promotes relaxation without sedation, improving attention and focus, particularly in combination with caffeine [8]. 1000 mg Organic Lion’s Mane: Supports brain health by stimulating nerve growth factors, which enhances memory and cognitive functions [12]. 150 mg Organic Bacopa Monnieri: Improves cognitive processing, memory, and learning speed by enhancing neurotransmitter activity and reducing anxiety [4]. Pricing 3-Pack (3-Month Supply): $93.60 User Reviews FOCL Day Stack seems promising on Amazon, snagging a 4.1 out of 5-star rating from over 20 reviews! Users appreciate the easy-to-swallow capsules and say it helps them feel focused, energized, and even in a better mood. However, some reviewers mentioned it just didn't work for them. Who Is Performance Lab Mind Best For? Performance Lab Mind is for you if you need an instant mental boost within 30 minutes . You might feel a surge of mental energy. And the longer you take it, the better it gets. So, if you’re also looking for the best nootropics for productivity, Performance Lab Mind might be worth a try. Key Ingredients 100 mg Phosphatidylserine: May improve memory, cognitive function, and mental clarity, especially under stress [13]. 250 mg L-Tyrosine: Boosts mental performance and focus, particularly during stressful or challenging situations [11]. 75 mg Maritime Pine Bark Extract: Supports brain health by improving blood flow and antioxidant protection [18]. Pricing Potential for mild side effects Who Is Mind Vitality Best For? Mind Vitality is best for individuals seeking a natural and holistic approach to cognitive enhancement and brain health. It's particularly suitable for adults of all ages who want to improve memory, focus, concentration, and mental clarity. Key Ingredients Mind Vitality boasts of its intriguing "Ignition Tri-Factor" formula, like a 3-pronged attack to help increase your brainpower. Each capsule packs a combo of effective nutrients working in 3 different ways to optimize your mental function. Let's explore some of the ingredients in each prong: Stress Kill Switch 250 mg Rhodiola Rosea: This enhances cognitive function and combats mental fatigue [19]. 300 mg Bacopa Monnieri: Helps improve memory and learning abilities [4]. 50 mg Ginkgo Biloba: Increases blood flow to the brain, supporting cognitive function and memory [21]. 0.2 mg Huperzia Serrate: May help boost neurotransmitter levels, enhancing memory and learning [22]. 500 mg Lion’s Mane: Stimulates nerve growth factor, promoting brain health and cognitive function [12]. Pricing Comes in only 2 flavors Who Is Neuro Gum Energy & Focus Best For? Neuro Gum Energy & Focus is your secret weapon for conquering busy days. Stuck in a brain fog? Feeling fried? Just pop a piece of this gum or mint for a quick and convenient mental boost! It's also reputed to be one of the best natural nootropics for on-the-go warriors who need to stay sharp, focused, and energized throughout the day. No need for pills or potions; just chew your way to better brain power. Key Ingredients 80 mg Natural Caffeine: Improves alertness and enhances focus, providing a quick mental boost [2]. 120 mg L-Theanine: Helps to promote relaxation without drowsiness, reducing stress and anxiety while enhancing cognitive function [8]. 1.4 mg Vitamin B6: Supports brain health and neurotransmitter function, improving mood and cognitive performance [20]. 4.8 mcg Vitamin B12: Boosts energy levels and aids in maintaining healthy brain functions [23]. Pricing Who Is BrainPill Best For? BrainPill is a one-stop shop for brainpower buffs. As one of the best nootropics for memory and mental clarity, this supplement is designed to be your brain's personal trainer. It may help you enhance your cognitive skills across the board . Imagine remembering things like a champ, getting a boost in short-term and long-term memory, and feeling sharper under pressure. You might find yourself concentrating more productively and getting more done in less time. Key Ingredients 100 mg L-Theanine: May help promote relaxation without drowsiness and improve focus and attention [8]. 250 mg Citicoline-Cognizin: This helps support brain energy, enhances memory, and boosts mental clarity [10]. 320 mg Bacopa Monnieri as Synapsa: Improves memory retention and cognitive function over time [4]. 100 mg Ginkgo Biloba: May help enhance blood flow to the brain, supporting cognitive function and memory [21]. Pricing Who Is BetterBrand BetterMushrooms Best For? If you're on the hunt for a mushroom-powered upgrade, BetterBrand BetterMushrooms might be your new best friend. This unique blend packs a punch with 12 functional mushrooms designed to help you relax, boost your mood, and sharpen your focus like a laser. In addition, it may improve your gut health and metabolism and keep inflammation and unfriendly microbes at bay. So, if you need the best nootropics for anxiety to level up your mind, body, and spirit, BetterBrand BetterMushrooms is definitely worth checking out! Key Ingredients Chaga: Enhances cognitive function and supports brain health with its high antioxidant content [24]. Reishi: Reduces stress and improves focus by promoting relaxation and mental clarity [25]. Turkey Tail: Supports immune function, which can contribute to overall brain health and mental performance [26]. Maitake: Boosts cognitive function and supports overall brain health with its rich nutrient profile [27]. Pricing Who Are Earth & Star Mushroom Gummies Best For? Looking to give your mental health a boost? Earth & Star Mushroom Gummies might be your new go-to! These brain-boosting gummies are packed with adaptogens, which are natural substances reputed to help your body handle stress . Plus, they're loaded with beta-glucans, which can be helpful for blood sugar control, keeping you feeling fuller for longer and supporting your immune system. Key Ingredients Earth and Star Mushroom Gummies include a total of 500 mg of fruiting body functional mushroom extracts per serving. Let’s look at a few of them: 500 mg Lion's Mane Mushroom: Enhances cognitive function and supports brain health by promoting nerve growth factor (NGF) production [12]. 200 mg L-Theanine: Promotes relaxation and reduces stress without causing drowsiness, improving focus and mental clarity [8]. Pricing User Reviews Folks on Amazon rave about the taste and say the nootropic is a fantastic way to keep your immune system strong. With an average of 4.3 stars out of 5 from over 100 reviews, these gummies seem like a winner. However, some users don’t like the raspberry flavor, and there are a few complaints about its cholesterol-raising ingredients. What Are Nootropics? Nootropics are like brain food for healthy folks looking to get a mental edge. Think of them as smart drugs or cognitive enhancers. The goal is to supercharge your brainpower. Nootropics can target areas like memory, creativity, and focus. They work in several different ways, like fine-tuning brain chemistry, boosting blood flow, or even encouraging brain cell growth. How Do Nootropics Work? Nootropics work through various mechanisms to enhance cognitive function and promote brain health. Some of the key ways they work include: Neurotransmitter Modulation Nootropics can influence the release, uptake, or sensitivity of brain chemicals like acetylcholine, dopamine, serotonin, and glutamate. This fancy footwork can have a real impact on your brainpower. By fine-tuning these brain chemicals, nootropics may help you learn better, recall things more easily, and concentrate like a champ. Enhancing Cerebral Circulation Imagine your brain cells are like partygoers. They need a steady stream of oxygen and nutrients to keep the party going strong, which is where nootropics that enhance cerebral circulation come in. These are like VIP passes for your brain cells. They work as vasodilators, increasing blood flow to deliver more oxygen and nutrients to your brain cells to help them function at their best. Neuroprotection Nootropics aren't just about giving your brain a temporary power-up. Some of them act like bodyguards for your brain cells. These neuroprotective nootropics are loaded with antioxidants and anti-inflammatory properties. They help shield your brain cells from damage caused by oxidative stress and inflammation. It's like putting up a shield to protect your brain from free radicals and inflammation. Increasing Neuroplasticity Some nootropics may help boost neuroplasticity, which is your brain's ability to “bend” and “reshape” itself. This can lead to some pretty awesome benefits, like improved learning, memory, and even better cognitive flexibility. Lion's mane mushroom and bacopa monnieri are some of the nootropics that are said to be particularly helpful in this area. Reducing Stress and Anxiety Feeling stressed and anxious can mess with your thinking, so some nootropics target your stress response and help you to relax. Adaptogens like ashwagandha and rhodiola rosea are some examples. They're thought to regulate cortisol levels, a stress hormone, and help prevent stress-related cognitive decline. Types of Nootropics Racetams These are one of the first classes synthetically created. Think of them as the granddaddies of smart drugs. Piracetam, aniracetam, and oxiracetam are some of the big names. They may help enhance your memory, learning rate, and overall brain function by tweaking your brain chemicals. Cholinergics They focus on a specific neurotransmitter called acetylcholine, which is like a messenger in your brain. Cholinergics, like choline supplements and huperzine A, can up the levels of this messenger molecule. Why? Because it's thought to help with memory and focus. So, giving your brain more of this communication tool might boost your cognitive abilities. Adaptogens They're all about helping your body adapt to stress and find its happy place. Ashwagandha, rhodiola rosea, and ginseng are some of the popular choices in this category. While they might not directly zap your brainpower like some other nootropics, they can indirectly help your cognitive function by fighting fatigue. Stimulants While they aren't your typical nootropics, they can be powerful tools for giving your brain a jumpstart. Stimulants can increase alertness, focus, and energy levels. But watch out for side effects and dependence. Neurotransmitter Precursors Nootropics can work in all sorts of ways to give your brain a boost, and here's where neurotransmitter precursors come in. They are building blocks for your brain chemicals, like dopamine, serotonin, and norepinephrine. The idea is that by providing your brain with more of this raw material, you might be able to support your mood, motivation, and even cognitive function. Natural Nootropics They come from herbs, plants, and even stuff you might already have in your kitchen, like caffeine. People have been using them for centuries, and they're generally considered to be safer options. Plus, some natural nootropics, like ginkgo biloba, might even give you other health benefits on top of the brain boost effect. Synthetic Nootropics On the other hand, synthetic nootropics are lab-made. You may think of them as cutting-edge tech for your brain. They're designed specifically to give you a cognitive edge, and some, like modafinil and racetams, can be really powerful. The downside? They can be harsher on your system and have more potential side effects. Are Nootropics Effective? So, the big question is whether nootropics actually work. Like most things in life, the answer is "it depends." Some people swear by nootropics, saying they've sharpened their focus, memory, and overall brainpower. For others, not so much. The truth is the science of nootropics is still playing catch-up. There have been some promising studies on certain compounds, but we need more research to know for sure how effective they are for different people and situations. Here's why it can be a mixed bag: Individual Biology: We're all wired differently, so what works wonders for your friend might not do much for you. Dosage: Like with any medication, dosage matters. Too little might not work, and too much could backfire. The Nootropic Itself: Some nootropics seem to have more scientific backing than others. The bottom line? Nootropics aren't magic pills. If you're considering trying them, it's important to do your research, talk to your doctor, and be realistic about your expectations. Short-Term Memory Struggling to remember where you put your keys? Short-term memory woes can be frustrating, but nootropics might be able to lend a helping hand. They come in different forms, but some supplements are packed with amino acids, the building blocks of protein. These amino acid powerhouses may potentially help maintain healthy nerve growth factors and brain connections. This could lead to sharper short-term memory and better information retention. Brain Health (Brain Cells) Keeping your brain cells happy and healthy is key to sharpening your thinking. Nootropics can potentially help with maintaining, developing, and even recovering brain cells. Let’s think of your brain cells as a garden. You want to keep them well-nourished and growing strong for optimal performance. Nootropics can be like fertilizer and sunshine for your brain garden. Focus and Productivity Stuck in a productivity rut? Nootropics might be the secret weapon you've been looking for. If you deal with demanding work or hobbies that require laser focus, these brain power boosters could be a game-changer. Nootropics contain natural ingredients that may help you crank up your output, sharpen your concentration, and zero in on those pesky details. They might even become your best friend if you pull long hours; some can combat fatigue and sleep deprivation, keeping you sharp even when you take them before bed. Improve Mental Performance Mental exhaustion and confusion are the two main symptoms that stress-induced disturbances in brain networks may cause. If you've observed a reduction in your cognitive skills, taking a nootropic pill daily may be a successful way to increase brain activity and return to normal. You may reach your full potential by using the best brain supplements to improve communication inside your cerebral circuits. Look for any of the best nootropics for brain fog, like Mind Lab Pro or Performance Lab Mind . Mood Regulation We all know life can throw curveballs that mess with our mood. The good news is some nootropics might be able to lend a hand. As mood regulators, they work by tweaking your brain chemistry and lessening the effects of imbalances that can lead to stress, anxiety, and even depression. In essence, the best nootropics rectify chemical imbalances in the brain and lessen their effects, which is how they might alleviate stress, anxiety, and depression. Consider supplements like Thesis or NooCube if you need the best nootropics for depression. Risks of Nootropics Nootropics, while offering potential cognitive benefits, also pose risks. Side Effects: Users may experience headaches, gastrointestinal issues, insomnia, or nervousness akin to other supplements or medications. Lack of Regulation: Many nootropics lack regulation by agencies like the FDA, raising concerns about safety and efficacy and increasing the risk of consuming contaminated or adulterated products. Dependency: Some individuals may develop a dependence on nootropics for cognitive enhancement, potentially relying on them for daily functioning or performance. Long-Term Effects: The jury's still out on what happens when you take nootropics for a long time, especially the synthetic or newer ones. How We Selected the Best Nootropic Brain Boosters Selecting the best nootropic brain boosters involves a rigorous process to ensure that the chosen products are effective and well-tolerated. Here are the key criteria and steps we used in our selection process: Customer Reviews Real user experiences offer valuable insights into a nootropic's effectiveness and potential side effects. We looked for consistent positive feedback regarding cognitive enhancement and minimal negative reports. Refund Policies A generous refund policy demonstrates a company's confidence in its product and allows you to try it risk-free. That is why we favored brands with transparent and hassle-free return windows. Dosage and Convenience Our review considered the dosage form (capsules, powder, etc.) and how often you need to take it. Look for convenient options that fit seamlessly into your routine and preference. Pricing and Availability Nootropics can vary in cost, so we considered both affordability and the value proposition relative to the ingredients and benefits offered. Easy availability from reputable retailers was also a plus. Ingredient Transparency and Efficacy We prioritized brands that disclose all ingredients clearly and prioritized those backed by scientific evidence for cognitive enhancement. We also favored nootropics with a clear focus on the desired effects. Safety and Quality Measures Manufacturing practices and third-party testing are crucial for ensuring the safety and purity of the ingredients. We prioritized brands that adhere to strict quality control measures. Brand Reputation and Authenticity Established nootropic brands have a history of transparency and positive customer feedback due to their proven quality and efficacy track record. Authenticity in marketing claims and adherence to ethical practices further enhance brand reputation, fostering consumer trust and loyalty. Here are answers to more popular questions people ask about the best nootropics online. Is It Safe to Use Smart Drugs? Smart drug safety depends on various factors, including individual health, product quality, and source, dosage, frequency of use, potential side effects, and long-term effects. Consult with a healthcare professional before starting any new supplement regimen. Use supplements judiciously, follow recommended guidelines, and monitor for adverse reactions. What Nootropics Work Right Away? Nootropics like caffeine and theacrine can give you that instant zap of focus and alertness you need. Even some adaptogens like rhodiola rosea or fast-absorbing herbal extracts can do the trick. Multi-ingredient formulas with fast-acting formulas include Performance Lab Mind and Mind Lab Pro . They usually start working within 30 minutes. But remember, everyone's different, and what works for some might not work for you. What Is the Highest Rated Brain Supplement? Finding the "highest-rated" brain booster is like finding the perfect jeans—it depends on what you need. Some folks love Thesis , NooCube , or Performance Lab Mind because they pack a punch with different ingredients and really seem to help them focus and remember. But remember, everyone's brain is wired differently, so do your research and chat with your doctor before trying any nootropics. Final Thoughts on the Best Nootropics In conclusion, if you're aiming to enhance your mental capabilities, nootropics might be worth exploring. This guide has reviewed 12 of the best options, including noteworthy products like Thesis , to help boost memory, focus, and overall cognitive function. Ideal for students, professionals, or anyone seeking a mental edge. These brain pills have been carefully selected based on their benefits, ingredients, and positive user feedback. With the right nootropic, you can potentially unlock a higher level of mental performance, making everyday cognitive tasks a bit easier to manage. 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Smith. “An Examination into the Mental and Physical Effects of a Saffron Extract (Affron®) in Recreationally-Active Adults: A Randomized, Double-Blind, Placebo-Controlled Study.” Journal of the International Society of Sports Nutrition, vol. 19, no. 1, 2022, pp. 219–238, doi:10.1080/15502783.2022.2083455. Huang, X., Gao, W., Yun, X., Qing, Z., & Zeng, J. (2022). Effect of natural antioxidants from marigolds (Tagetes erecta L.) on the oxidative stability of soybean oil. Molecules (Basel, Switzerland), 27(9), 2865. https://doi.org/10.3390/molecules27092865 Baba, Yoshitake, et al. “Effects of L-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.” Journal of Medicinal Food, vol. 24, no. 4, 2021, pp. 333–341, doi:10.1089/jmf.2020.4803. Jakaria, Md, et al. “Active Ginseng Components in Cognitive Impairment: Therapeutic Potential and Prospects for Delivery and Clinical Study.” Oncotarget, vol. 9, no. 71, 2018, pp. 33601–33620, doi:10.18632/oncotarget.26035. M. Al-kuraishy, Hayder, and Ali I. Al-Gareeb. “Citicoline Improves Human Vigilance and Visual Working Memory: The Role of Neuronal Activation and Oxidative Stress.” Basic and Clinical Neuroscience, vol. 11, no. 4, 2020, p. 423, doi:10.32598/bcn.11.4.1097.1. Jongkees, Bryant J., et al. “Effect of Tyrosine Supplementation on Clinical and Healthy Populations under Stress or Cognitive Demands—A Review.” Journal of Psychiatric Research, vol. 70, 2015, pp. 50–57, doi:10.1016/j.jpsychires.2015.08.014. Docherty, Sarah, et al. “The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study.” Nutrients, vol. 15, no. 22, 2023, p. 4842, doi:10.3390/nu15224842. Glade, Michael J., and Kyl Smith. “Phosphatidylserine and the Human Brain.” Nutrition (Burbank, Los Angeles County, Calif.), vol. 31, no. 6, 2015, pp. 781–786, doi:10.1016/j.nut.2014.10.014. Ostrovskaia, R. U., and S. S. Trofimov. “Nootropic Properties of Gamma-Aminobutyric Acid Derivatives.” Biulleten’ Eksperimental’noi Biologii i Meditsiny, vol. 97, no. 2, 1984, https://pubmed.ncbi.nlm.nih.gov/6538101/. Sabelli, H. C., and J. I. Javaid. “Phenylethylamine Modulation of Affect: Therapeutic and Diagnostic Implications.” The Journal of Neuropsychiatry and Clinical Neurosciences, vol. 7, no. 1, 1995, pp. 6–14, doi:10.1176/jnp.7.1.6. Catalani, Valeria, et al. “Octodrine: New Questions and Challenges in Sport Supplements.” Brain Sciences, vol. 8, no. 2, 2018, p. 34, doi:10.3390/brainsci8020034. Al-Kuraishy, H. M., & Al-Gareeb, A. I. (2020). Citicoline improves human vigilance and visual working memory: The role of neuronal activation and oxidative stress. Basic and Clinical Neuroscience, 11(4), 423–432. https://doi.org/10.32598/bcn.11.4.1097.1 Belcaro, G., et al. “Pycnogenol® Improves Cognitive Function, Attention, Mental Performance and Specific Professional Skills in Healthy Professionals Aged 35-55.” Journal of Neurosurgical Sciences, vol. 58, no. 4, 2014, https://pubmed.ncbi.nlm.nih.gov/24675223/. Ma, Gou-Ping, et al. “Rhodiola Rosea L. Improves Learning and Memory Function: Preclinical Evidence and Possible Mechanisms.” Frontiers in Pharmacology, vol. 9, 2018, doi:10.3389/fphar.2018.01415. Field, David T., et al. “High‐dose Vitamin B6 Supplementation Reduces Anxiety and Strengthens Visual Surround Suppression.” Human Psychopharmacology, vol. 37, no. 6, 2022, doi:10.1002/hup.2852. Lee, Helen, and Jacqueline S. Birks. “Ginkgo Biloba for Cognitive Improvement in Healthy Individuals.” The Cochrane Library, vol. 2018, no. 8, 2018, doi:10.1002/14651858.cd004671.pub2. Zangara, Andrea. “The Psychopharmacology of Huperzine A: An Alkaloid with Cognitive Enhancing and Neuroprotective Properties of Interest in the Treatment of Alzheimer’s Disease.” Pharmacology, Biochemistry, and Behavior, vol. 75, no. 3, 2003, pp. 675–686, doi:10.1016/s0091-3057(03)00111-4. Markun, Stefan, et al. “Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.” Nutrients, vol. 13, no. 3, 2021, p. 923, doi:10.3390/nu13030923. Giridharan, Vijayasree Vayalanellore, et al. “Amelioration of Scopolamine Induced Cognitive Dysfunction and Oxidative Stress by Inonotus Obliquus– a Medicinal Mushroom.” Food & Function, vol. 2, no. 6, 2011, p. 320, doi:10.1039/c1fo10037h. Kuo, Hui-Chuan, et al. “Ganoderma Tsugae Prevents Cognitive Impairment and Attenuates Oxidative Damage in D-Galactose-Induced Aging in the Rat Brain.” PloS One, vol. 17, no. 4, 2022, p. e0266331, doi:10.1371/journal.pone.0266331. Benson, Kathleen F., et al. “The Mycelium of the Trametes Versicolor (Turkey Tail) Mushroom and Its Fermented Substrate Each Show Potent and Complementary Immune Activating Properties in Vitro.” BMC Complementary and Alternative Medicine, vol. 19, no. 1, 2019, doi:10.1186/s12906-019-2681-7. Mayell, M. (2001). Maitake extracts and their therapeutic potential. Alternative Medicine Review: A Journal of Clinical Therapeutic, 6(1), 48–60. https://pubmed.ncbi.nlm.nih.gov/11207456/

Thesis Frequently Asked Questions (FAQ)

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Thesis was founded in 2017.

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Thesis's headquarters is located at 902 Broadway, New York.

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Thesis's latest funding round is Series A.

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Thesis raised a total of $8.4M.

Who are the investors of Thesis?

Investors of Thesis include REDO Ventures, Kevin Love, Alive Israel HealthTech Fund, Kate Bock, Unilever Ventures and 5 more.

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Overview of the Russian supplement market Overview of the Russian supplement market

Russia requires biologically active supplements (BAS) to be registered before they enter the market, which is a complicated and expensive process.

October 31, 2016

Central and Eastern Europe is the most promising region in the dietary supplement market with average growth of more than 15 percent. The biggest market in this region is Russia, where dietary supplements are termed biologically active supplements (BASs). According to a U.S. Commercial Services report, industry experts claim the sale of BASs in Russian pharmacies was US$845 million in 2013 in wholesale prices, and $1.17 billion at retail.

According to the marketing agency Comcon-Pharma, BAS products in Russia are only used by 20 percent of consumers, which is significantly lower than in Europe and the United States, which have rates of 50 and 80 percent, respectively. However, consumption of BAS products are on the rise in Russia due to work and life pressures. The major BAS product categories focus on enhancing the immune system, improving overall health and preventing disease.

The Russian government is working to make the BAS market more transparent with stricter regulations for the registration process and distribution channel.

History and definition

BASs officially appeared in Russia in 1994, when the Ministry of Health started registering them as a separate group of substances. Since 1998, BASs have been actively promoted on the Russian market.

Consumers can take BASs in the form of tablets, capsules, syrups and powders. According to Technical Regulations “ About Safety of Foods " (Article 24, TP TC 021/2011), BASs, with natural and/or identical to natural biologically active ingredients, and also probiotic microorganisms, are intended for consumption with food or inclusion in products to enrich the diet with them.

According to the definition, the following products can be identified as a BAS:

Polysaturated acids

Mineral substances, micro and macro elements

Some amino acids

Some mono and disaccharides

Food fibers

Microorganisms present in human body

Vitamins, subject to upper limits

Registration

Russia has required mandatory registration for BAS products since 2004. The registration is one of the biggest obstacles for BASs entering the Russian market. In order to sell BASs on the Russian market, a manufacturer/distributor needs a certificate of state registration used for both customs clearance and distribution in Russia, which is issued by the Federal Service for Supervision of Consumer Rights Protection and Human Welfare.

The procedure includes three stages:

Analysis of provided documents,

Tests (microbiological; toxicological; and herbal BAS require tests for pesticides, identity and, in some cases tests for genetically modified ingredients), and

Issuance of certificate of state registration.

Before starting the process of registration, a manufacturer should keep in mind that:

Not every BAS can be registered in Russia despite holding all registration documents in the country of origin;

A set of documents used for the registration in the country of origin is not always enough for the registration authorities in Russia;

The full list of proposed medical use approved in the country of origin could be approved only partially by the Russian registration authorities; and

Each BAS should have its own certificate of registration, even if the only difference is its flavor.

In Russia, the registration procedure is complicated and expensive, and the required documents are constantly changing because of the complicated regulatory requirement. In order to successful accomplish registration of BAS products in Russia, it is recommended that brands work with a reliable partner. These could include a company incorporated in Russia with a U.S. parent company, a Russian distributor or authorized agent, or a consulting company.

Distribution channel

The three major distribution channels selling BAS products in Russia are pharmacies, retail stores and direct sales, including multi-level marketing (MLM). At present, MLM distribution is booming in Russia, growing by 30 percent year-on-year, and BASs account for 2 percent of sales (the remaining are cosmetics and various consumer goods), according to Euromonitor International.

Distribution of BAS in Russia is only permitted through pharmacies and authorized stores.

This information is for reference only. It has no legal value. Davidia Healthtech LLC declines all responsibility or liability for errors or deficiencies in this document. Authorities in various countries have the right to determine a product’s regulatory status. Laws and the related guidance change constantly. We cannot guarantee regulations referred to in the document remain unchanged. The text should not be taken as an authoritative statement or interpretation of the law, as only the courts have this power. Every effort has been made to ensure these guidance notes are as helpful as possible.

Hua Deng, Ph.D., is the president and the founder of Davidia Healthtech LLC , a professional service company for food, dietary supplement and cosmetics. Deng holds a doctorate from Lanzhou University in China with a major in analytical chemistry. She has extensive experience with global regulatory affairs in the food, dietary supplement and cosmetic industries.

About the Author

Hua Deng, Ph.D., is the president and the founder of Davidia Healthtech LLC, a professional service company for food, dietary supplement and cosmetics. Deng holds a doctorate from Lanzhou University in China with a major in analytical chemistry. She has extensive experience of global regulatory affairs in the food, dietary supplement and cosmetic industries.

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Bioavailable form of uridine necessary for healthy nerve cell membranes and function.

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Zembrin® has been shown to improve in mood and disposition.

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You will receive our Logic formulation to lock in on the task at hand, with an emphasis on supporting memory and retention. This order includes a four week supply of nootropics, an instructional booklet, and access to our team of experts and wellness coaches to help you set and achieve your goals!

You will also receive email messages with additional instructions to make the most of this exploratory month.

We offer the most advanced nootropic system available, to find the exact compliment for your specific brain chemistry and desired areas of focus.

Our innovative Starter Kit allows you to experience multiple formulations, and determine what works best. Our process is complex because we’ve found that it yields the best results in the shortest amount of time.

If we could formulate one pill that would work for everyone, we would! Because the human brain is deeply complex, that is just not possible.

Depending on your genetics and experience with nootropics, the effects can be felt in as little as 30 minutes after taking each blend.

Nootropics have the most impact when taken on an empty stomach, just after waking from a normal night of rest.

Some people may need a few days of consecutive use to feel the effects of the nutrients.

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